A1A3A5 · PDXS_BIFAA

Function

function

Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.

Catalytic activity

Pathway

Cofactor biosynthesis; pyridoxal 5'-phosphate biosynthesis.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site23D-ribose 5-phosphate (UniProtKB | ChEBI)
Active site80Schiff-base intermediate with D-ribose 5-phosphate
Binding site152D-ribose 5-phosphate (UniProtKB | ChEBI)
Binding site164D-glyceraldehyde 3-phosphate (UniProtKB | ChEBI)
Binding site213D-ribose 5-phosphate (UniProtKB | ChEBI)
Binding site234-235D-ribose 5-phosphate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionpyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity
Biological Processamino acid metabolic process
Biological Processpyridoxal phosphate biosynthetic process
Biological Processpyridoxine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Pyridoxal 5'-phosphate synthase subunit PdxS
  • EC number
  • Short names
    PLP synthase subunit PdxS
  • Alternative names
    • Pdx1

Gene names

    • Name
      pdxS
    • Ordered locus names
      BAD_1407

Organism names

Accessions

  • Primary accession
    A1A3A5

Proteomes

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10000703651-291Pyridoxal 5'-phosphate synthase subunit PdxS

Proteomic databases

Interaction

Subunit

In the presence of PdxT, forms a dodecamer of heterodimers.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the PdxS/SNZ family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    291
  • Mass (Da)
    31,180
  • Last updated
    2007-01-23 v1
  • Checksum
    65AC5BC41B75930E
MANNRNELNKNLAQMLKGGVIMDVTTPEQAKIAQDAGACAVMALERIPADIRAAGGVSRMSDPAMIKGIQEAVSIPVMAKVRIGHIAEARILQAIEIDYIDESEVLSPADDVYHIDKNRFDVPFVCGAKNLGEALRRVAEGASMIRTKGEPGTGDVIQAVRHMRTMNKQIRELVSLRDDEVYEAAKQLAVPYDLAKYVHDNGRLPVVNFAAGGVATPADAALMMELGAEGVFVGSGIFKSGDPAKRAAAIVQATANWQDAELLARLSENLGEAMVGINEDEIETIMAARGE

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP009256
EMBL· GenBank· DDBJ
BAF40188.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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