miR-200c/141 Regulates Breast Cancer Stem Cell Heterogeneity via Targeting HIPK1/beta-Catenin Axis.
- AnnotationThe miR-200c/141 cluster regulated breast cancer stem cells heterogeneity and promoted the epithelial-mesenchymal transformation-like breast cancer stem cells generation which resulted in increased tumor metastasis and inhibited tumor growth by directly upregulating the target gene homeodomain-interacting protein kinase 1 (HIPK1) and sequential beta-catenin activation.
- CategoriesFunction, Expression