A0QSU7 · A0QSU7_MYCS2
- Proteinacetolactate synthase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids537 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
Catalytic activity
- 2 pyruvate + H+ = (2S)-2-acetolactate + CO2
Pathway
Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 1/4.
Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 1/4.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 434 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 461 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 463 | Mg2+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | acetolactate synthase activity | |
Molecular Function | benzoylformate decarboxylase activity | |
Molecular Function | flavin adenine dinucleotide binding | |
Molecular Function | magnesium ion binding | |
Molecular Function | thiamine pyrophosphate binding | |
Biological Process | isoleucine biosynthetic process | |
Biological Process | valine biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameacetolactate synthase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Mycobacteriales > Mycobacteriaceae > Mycolicibacterium
Accessions
- Primary accessionA0QSU7
Proteomes
PTM/Processing
Proteomic databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 6-107 | Thiamine pyrophosphate enzyme N-terminal TPP-binding | |||
Domain | 191-325 | Thiamine pyrophosphate enzyme central | |||
Domain | 390-527 | Thiamine pyrophosphate enzyme TPP-binding | |||
Sequence similarities
Belongs to the TPP enzyme family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length537
- Mass (Da)57,154
- Last updated2007-01-09 v1
- Checksum44A043F3F71991C0
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000480 EMBL· GenBank· DDBJ | ABK72223.1 EMBL· GenBank· DDBJ | Genomic DNA |