A0QQK1 · ACKA_MYCS2

Function

function

Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Note: Mg2+. Can also accept Mn2+.

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2.

Features

Showing features for binding site, active site, site.

TypeIDPosition(s)Description
Binding site7Mg2+ (UniProtKB | ChEBI)
Binding site14ATP (UniProtKB | ChEBI)
Binding site71substrate
Active site128Proton donor/acceptor
Site160Transition state stabilizer
Binding site188-192ATP (UniProtKB | ChEBI)
Site221Transition state stabilizer
Binding site262-264ATP (UniProtKB | ChEBI)
Binding site310-314ATP (UniProtKB | ChEBI)
Binding site364Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionacetate kinase activity
Molecular FunctionATP binding
Molecular Functionmagnesium ion binding
Biological Processacetate metabolic process
Biological Processacetyl-CoA biosynthetic process
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Acetate kinase
  • EC number
  • Alternative names
    • Acetokinase

Gene names

    • Name
      ackA
    • Ordered locus names
      MSMEG_0784, MSMEI_0768

Organism names

Accessions

  • Primary accession
    A0QQK1

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004219481-376Acetate kinase

Proteomic databases

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the acetokinase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    376
  • Mass (Da)
    40,116
  • Last updated
    2007-01-09 v1
  • Checksum
    5F9BBCA380D2A161
MTVLVVNSGSSSLKYAVVRPASGEFLADGIIEEIGSGAVPDHDAALRAAFDELAAAGLHLEDLDLKAVGHRMVHGGKTFYKPSVVDDELIAKARELSPLAPLHNPPAIKGIEVARKLLPDLPHIAVFDTAFFHDLPAPASTYAIDRELAETWHIKRYGFHGTSHEYVSQQAAIFLDRPLESLNQIVLHLGNGASASAVAGGKAVDTSMGLTPMEGLVMGTRSGDIDPGVIMYLWRTAGMSVDDIESMLNRRSGVLGLGGASDFRKLRELIESGDEHAKLAYDVYIHRLRKYIGAYMAVLGRTDVISFTAGVGENVPPVRRDALAGLGGLGIEIDDALNSAKSDEPRLISTPDSRVTVLVVPTNEELAIARACVGVV

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000480
EMBL· GenBank· DDBJ
ABK74906.1
EMBL· GenBank· DDBJ
Genomic DNA
CP001663
EMBL· GenBank· DDBJ
AFP37248.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp