A0LCI9 · A0LCI9_MAGMM
- ProteinHypoxanthine phosphoribosyltransferase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids184 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- diphosphate + GMP = 5-phospho-alpha-D-ribose 1-diphosphate + guanineThis reaction proceeds in the backward direction.
Cofactor
Pathway
Purine metabolism; IMP biosynthesis via salvage pathway; IMP from hypoxanthine: step 1/1.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | guanine phosphoribosyltransferase activity | |
Molecular Function | hypoxanthine phosphoribosyltransferase activity | |
Molecular Function | magnesium ion binding | |
Molecular Function | nucleotide binding | |
Biological Process | GMP salvage | |
Biological Process | guanine salvage | |
Biological Process | hypoxanthine metabolic process | |
Biological Process | IMP salvage | |
Biological Process | purine ribonucleoside salvage |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameHypoxanthine phosphoribosyltransferase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Magnetococcales > Magnetococcaceae > Magnetococcus
Accessions
- Primary accessionA0LCI9
Proteomes
Subcellular Location
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 18-164 | Phosphoribosyltransferase | ||||
Sequence: KIQRRVQALAKEIIARMGQEPVMVALLKGSFLFAADLLREMGRQGAKPKLDFLAVSSYGSGTQSTGQVQVQLAIKEPLQGRDVLLVDDILDTGNTFAHVIELLKAQGAQQVLTCTLLNKQARRQQPVVADFIGFEVPDAFVVGYGID |
Sequence similarities
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length184
- Mass (Da)20,237
- Last updated2006-12-12 v1
- Checksum19358BD0E2F18916
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000471 EMBL· GenBank· DDBJ | ABK45682.1 EMBL· GenBank· DDBJ | Genomic DNA |