A0KZB1 · NADK_SHESA
- ProteinNAD kinase
- GenenadK
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids309 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
Catalytic activity
- ATP + NAD+ = ADP + H+ + NADP+
Cofactor
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 89 | Proton acceptor | ||||
Sequence: D | ||||||
Binding site | 89-90 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: DG | ||||||
Binding site | 163-164 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: NE | ||||||
Binding site | 174 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: H | ||||||
Binding site | 191 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 193 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 204-209 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: TAYALS |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Molecular Function | NAD binding | |
Molecular Function | NAD+ kinase activity | |
Biological Process | NAD metabolic process | |
Biological Process | NADP biosynthetic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameNAD kinase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Alteromonadales > Shewanellaceae > Shewanella
Accessions
- Primary accessionA0KZB1
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_1000079516 | 1-309 | NAD kinase | |||
Sequence: MGINFDVSRPKARSSINMTTKFHTIGLIGKPHHPGTNQTLKRLHHWLTVQGYEVLVEERVASELGTNIIAVDLLEIGARCDLAIVVGGDGNMLGAARVLARFDVGVIGVNRGNLGFLTDLPPDAFEEALAKVLDGEFDTEHRFLLEAEVYRHGMLKASNTAVNEAVLHPGKIAHMIEFEVYIDNQFMYSQRADGMIVSTPTGSTAYALSAGGAILTPNLQALILVPMFPHTLSCRPIVVDACSTIKMVVSPENGENLEVSCDGHVHLAVLPGDEIIVRRSSEQLRLIHPKGHNYFHVLRSKLGWGSKLF |
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length309
- Mass (Da)33,773
- Last updated2006-12-12 v1
- Checksum20FEB715F352BC14
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000469 EMBL· GenBank· DDBJ | ABK49130.1 EMBL· GenBank· DDBJ | Genomic DNA |