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A0KK76 · FADI_AERHH

Function

function

Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.

Catalytic activity

Pathway

Lipid metabolism; fatty acid beta-oxidation.

Features

Showing features for active site.

143650100150200250300350400
TypeIDPosition(s)Description
Active site99Acyl-thioester intermediate
Active site392Proton acceptor
Active site422Proton acceptor

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionacetyl-CoA C-acyltransferase activity
Biological Processfatty acid beta-oxidation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    3-ketoacyl-CoA thiolase
  • EC number
  • Alternative names
    • ACSs
    • Acetyl-CoA acyltransferase
    • Acyl-CoA ligase
    • Beta-ketothiolase
    • Fatty acid oxidation complex subunit beta

Gene names

    • Name
      fadI
    • Ordered locus names
      AHA_2153

Organism names

Accessions

  • Primary accession
    A0KK76

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10000694921-4363-ketoacyl-CoA thiolase

Interaction

Subunit

Heterotetramer of two alpha chains (FadJ) and two beta chains (FadI).

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the thiolase-like superfamily. Thiolase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    436
  • Mass (Da)
    46,427
  • Last updated
    2006-12-12 v1
  • MD5 Checksum
    E9380B587AB23AD6F65E75500D5672E8
MKEPLKLTTRQGERIAVVAGLRTPFAKQATAFHGVPAVDLGKLVVSEMLARTDLDPKLIDQLVFGQVVQMPEAPNIAREIVLGTGMSVSTDAYSVSRACATSFQAVANVTESIMAGTVDIAIAGGADSSSVLPIGVSKKLARALVDLNKARNLQQRFNILRQLRVKDLLPVPPAVAEYSTGLSMGQTAEQMAKSHQISREAQDALAHRSHTLAAQAWADGKLSGEVFTAHVPPYKAPLERDNNIRESSDLASYAKLKPVFDRVHGSVTAANATPLTDGAAAVLLMREGRARELGLEPLGYIRSFAFSAIDVWQDMLMGPSYATPLALDRAGITLSDLTLIDMHEAFAAQTLANLKMFASKEFAQSKLGRDQAIGEVDMDKFNVLGGSLAFGHPFAATGARMITQTLHELRRRGGGLGLNTACAAGGLGVAMVLEVE

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000462
EMBL· GenBank· DDBJ
ABK38830.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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