A0KH11 · ALR_AERHH
- ProteinAlanine racemase
- Genealr-1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids357 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
function
Catalyzes the interconversion of L-alanine and D-alanine. Likely plays an important role in supplying D-alanine, which is an indispensable constituent in the biosynthesis of bacterial cell-wall peptidoglycan.
Catalytic activity
- L-alanine = D-alanine
Cofactor
Pathway
Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1.
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 34 | Proton acceptor; specific for D-alanine | ||||
Sequence: K | ||||||
Binding site | 129 | substrate | ||||
Sequence: R | ||||||
Active site | 254 | Proton acceptor; specific for L-alanine | ||||
Sequence: Y | ||||||
Binding site | 302 | substrate | ||||
Sequence: M |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | alanine racemase activity | |
Molecular Function | pyridoxal phosphate binding | |
Biological Process | D-alanine biosynthetic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAlanine racemase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Aeromonadales > Aeromonadaceae > Aeromonas
Accessions
- Primary accessionA0KH11
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for chain, modified residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000446937 | 1-357 | Alanine racemase | |||
Sequence: MKAAIAQINTAALRHNLAVVKRHAPQCKIIAVVKANAYGHGLLPVARTLVDADAYAVARIEEALMLRSCAVVKPIVLLEGFFSAADLPVLAANNLQTAVHTWEQLEALEQADLPAPVVAWLKLDTGMHRLGVRADEMPAFIERLAKCKNVVQPFNIMTHFSRSDELEQPTTREQIDLFSQLTAPLLGERAMANSAGILAWPDSHCDWVRPGVILYGVSPFPNTVAADYDLQPVMTLKTQLIAVRDHKAGEPVGYGANWVSDRDTRLGVIAIGYGDGYPRMAPNGTPVLVNGRIVPLVGRVSMDMTTVDLGPGATDKAGDEAVLWGEGLPVERVADQIGTIPYELITKLTSRVFMEYV | ||||||
Modified residue | 34 | N6-(pyridoxal phosphate)lysine | ||||
Sequence: K |
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length357
- Mass (Da)38,774
- Last updated2006-12-12 v1
- Checksum8C552F85D7AF5CD9
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000462 EMBL· GenBank· DDBJ | ABK36160.1 EMBL· GenBank· DDBJ | Genomic DNA |