A0KH11 · ALR_AERHH

Function

function

Catalyzes the interconversion of L-alanine and D-alanine. Likely plays an important role in supplying D-alanine, which is an indispensable constituent in the biosynthesis of bacterial cell-wall peptidoglycan.

Catalytic activity

Cofactor

pyridoxal 5'-phosphate (UniProtKB | Rhea| CHEBI:597326 )

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1.

Features

Showing features for active site, binding site.

TypeIDPosition(s)Description
Active site34Proton acceptor; specific for D-alanine
Binding site129substrate
Active site254Proton acceptor; specific for L-alanine
Binding site302substrate

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionalanine racemase activity
Molecular Functionpyridoxal phosphate binding
Biological ProcessD-alanine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Alanine racemase
  • EC number

Gene names

    • Name
      alr-1
    • Ordered locus names
      AHA_1015

Organism names

Accessions

  • Primary accession
    A0KH11

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for chain, modified residue.

TypeIDPosition(s)Description
ChainPRO_00004469371-357Alanine racemase
Modified residue34N6-(pyridoxal phosphate)lysine

Interaction

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the alanine racemase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    357
  • Mass (Da)
    38,774
  • Last updated
    2006-12-12 v1
  • Checksum
    8C552F85D7AF5CD9
MKAAIAQINTAALRHNLAVVKRHAPQCKIIAVVKANAYGHGLLPVARTLVDADAYAVARIEEALMLRSCAVVKPIVLLEGFFSAADLPVLAANNLQTAVHTWEQLEALEQADLPAPVVAWLKLDTGMHRLGVRADEMPAFIERLAKCKNVVQPFNIMTHFSRSDELEQPTTREQIDLFSQLTAPLLGERAMANSAGILAWPDSHCDWVRPGVILYGVSPFPNTVAADYDLQPVMTLKTQLIAVRDHKAGEPVGYGANWVSDRDTRLGVIAIGYGDGYPRMAPNGTPVLVNGRIVPLVGRVSMDMTTVDLGPGATDKAGDEAVLWGEGLPVERVADQIGTIPYELITKLTSRVFMEYV

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000462
EMBL· GenBank· DDBJ
ABK36160.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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