A0KEL3 · PEPQ_AERHH
- ProteinXaa-Pro dipeptidase
- GenepepQ
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids440 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Splits dipeptides with a prolyl residue in the C-terminal position.
Catalytic activity
- H2O + Xaa-L-Pro dipeptide = an L-alpha-amino acid + L-proline
Cofactor
Note: Binds 2 manganese ions per subunit.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 246 | Mn2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 257 | Mn2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 257 | Mn2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 337 | Mn2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: H | ||||||
Binding site | 382 | Mn2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 421 | Mn2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 421 | Mn2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: E |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | metal ion binding | |
Molecular Function | metalloexopeptidase activity | |
Molecular Function | phosphoric triester hydrolase activity | |
Molecular Function | proline dipeptidase activity | |
Biological Process | proteolysis |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Protein family/group databases
Names & Taxonomy
Protein names
- Recommended nameXaa-Pro dipeptidase
- EC number
- Short namesX-Pro dipeptidase
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Aeromonadales > Aeromonadaceae > Aeromonas
Accessions
- Primary accessionA0KEL3
Proteomes
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000303837 | 1-440 | Xaa-Pro dipeptidase | |||
Sequence: MSSYSQLFAQHLDTLQQRTRDILQQQGLSGLAIHSGQTHRIFLDDQDYPFKVNPQFKAWLPVLDNPHCWLLVDGVNKPVLLFYRPVDFWHKVAELPNAFWVDFFDIRFLTRPEQVADHLPANKQEWAYLGGHLEVAELLGLGQPNPEAVLNYLHYHRAYKTAYELECLRDANRIGVRGHIAAKDSFMAGASEFEINLAYMKAVGQGANEAPYGNIVAINRNAAILHYTHLSAQRVPDAERYSFLIDAGVDVHGYASDITRTWAWRRGEFADLIAALDAQQQEIIEEIKPGRRYSELHLQMHHRLARLLQATELVDMSVDEMIHTGVTNVFFPHGLGHFLGLQVHDAGGFMQDERGTHLSAPEQFPYLRCTRVMEVGQVFTIEPGLYFIDSLLEPLRLGEQGKRVNWNKVEALRPYGGIRIEDNVVLHANGVENLTRQAGL |
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length440
- Mass (Da)50,049
- Last updated2006-12-12 v1
- Checksum89AFC06646CB643D
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000462 EMBL· GenBank· DDBJ | ABK36051.1 EMBL· GenBank· DDBJ | Genomic DNA |