A0JQ18 · SOP14_ARATH

Function

function

Brassicaceae-specific phytocytokine (plant endogenous peptide released into the apoplast) perceived by MIK2 in a BAK1/SERK3 and SERK4 coreceptors-dependent manner, that modulates various physiological and antimicrobial processes including growth prevention and reactive oxygen species (ROS) response regulation (PubMed:31001913, PubMed:33514716, PubMed:34535661).
Inhibits root growth and regulates root meristems (PubMed:31001913, PubMed:34535661).
Prevents general growth and development (PubMed:31001913).
Exhibits antibacterial effects against Pseudomonas syringae pv. tomato DC3000, Ralstonia solanacearum, Bacillus subtilis and Agrobacterium tumefaciens, thus being an antimicrobial peptide (AMP) (PubMed:31001913).

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentapoplast
Cellular Componentplasma membrane
Molecular FunctionLRR domain binding
Molecular Functionreceptor serine/threonine kinase binding
Biological Processdefense response
Biological Processdefense response to bacterium
Biological Processresponse to bacterium
Biological Processresponse to cold
Biological Processresponse to ethylene
Biological Processresponse to jasmonic acid
Biological Processresponse to salicylic acid
Biological Processresponse to salt stress
Biological Processresponse to water deprivation

Names & Taxonomy

Protein names

  • Recommended name
    Serine rich endogenous peptide 14
  • Short names
    AtSCOOP14
  • Alternative names
    • Phytocytokine SCOOP14
    • Precursor of serine rich endogenous peptide phytocytokine 14
    • Secreted transmembrane peptide 2

Gene names

    • Name
      PROSCOOP14
    • Synonyms
      SCOOP14
      , STMP2
    • ORF names
      F19G10.22
    • Ordered locus names
      At1g22890

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    A0JQ18

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Cell membrane
Note: The precursor of SCOOP14, PROSCOOP14, accumulates at the plasma membrane and is proteolytically cleaved to release the SCOOP14 in the apoplasm.

Keywords

Phenotypes & Variants

Disruption phenotype

Slightly increased growth and fresh weight.

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 12 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for peptide, signal, propeptide.

TypeIDPosition(s)Description
PeptidePRO_0000457241?-73Serine rich endogenous peptide 14
Signal1-31
PropeptidePRO_000045724032-?Removed in mature form

Keywords

Proteomic databases

Expression

Tissue specificity

Mostly expressed in seedlings shoots and leaves, and, to a lower extent, in roots, stems, siliques, seeds and flowers.

Induction

Induced by cold, drought and salt stress, but repressed by pathogenic bacteria Pseudomonas syringae pv. tomato (Pst) DC3000, jasmonate (MeJA), ethylene (ET) and salicylic acid (SA), mainly in shoots.

Gene expression databases

Interaction

Subunit

Interacts with MIK2 (via extracellular leucine-rich repeat domain); this interaction triggers the formation of complex between MIK2 and the BAK1/SERK3 and SERK4 coreceptors, and subsequent BAK1 activation by phosphorylation.

Family & Domains

Features

Showing features for region, compositional bias, motif.

TypeIDPosition(s)Description
Region44-73Disordered
Compositional bias45-59Pro residues
Motif59-73SCOOP motif
Motif65-67SxS motif essential for MIK2 binding

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    73
  • Mass (Da)
    7,777
  • Last updated
    2011-05-03 v1
  • Checksum
    F5709EE31805D910
MAAKTSNLVALLLSLFLLLLSISSQVGLGEAKRNLRNNLRLDCVSHPSPPPPHRSMAPPIFVPPSTSHKGQGP

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias45-59Pro residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF000657
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
CP002684
EMBL· GenBank· DDBJ
AEE30304.1
EMBL· GenBank· DDBJ
Genomic DNA
BT029388
EMBL· GenBank· DDBJ
ABK32202.1
EMBL· GenBank· DDBJ
mRNA
AK317242
EMBL· GenBank· DDBJ
BAH19923.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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