A0AAQ4CNG3 · A0AAQ4CNG3_9CREN

  • Protein
    Orotidine 5'-phosphate decarboxylase
  • Gene
    pyrF
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).

Catalytic activity

Pathway

Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2.

Features

Showing features for binding site, active site.

121920406080100120140160180200
Type
IDPosition(s)Description
Binding site10substrate
Binding site29substrate
Binding site58-67substrate
Active site60Proton donor
Binding site114substrate
Binding site163-173substrate
Binding site186substrate
Binding site187substrate

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Orotidine 5'-phosphate decarboxylase
  • EC number
  • Alternative names
    • OMP decarboxylase
      (OMPDCase
      ; OMPdecase
      )

Gene names

    • Name
      pyrF
    • ORF names
      SACC_03610

Organism names

  • Taxonomic identifier
  • Strain
    • JCM32116
  • Taxonomic lineage
    Archaea > Thermoproteota > Thermoprotei > Sulfolobales > Sulfolobaceae > Saccharolobus

Accessions

  • Primary accession
    A0AAQ4CNG3

Proteomes

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain4-202Orotidine 5'-phosphate decarboxylase

Sequence similarities

Belongs to the OMP decarboxylase family. Type 1 subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    219
  • Mass (Da)
    24,235
  • Last updated
    2024-10-02 v1
  • Checksum
    574FBB9D09835216
MKNRVILAMDKYIPLEILSEIESEVYGLKIGLPLVLDLGLEKVRNLVKEVNIEEIIVDFKLADIGYVMKSVVEKMLFADSFIAHSFIGVKGSLDELKSYLDEKGKGLYLVASMSHSGWNNSFLSYIKEVIKEINPKGIVIGATKTDLISSFKREFSSIKIISPGVGVQGANYGDAICAGADFEIIGRSIYTAKDPVNQLKSINKIIEDRVMNCKGRVPK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP025226
EMBL· GenBank· DDBJ
BDB97344.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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