A0AAP9E7H5 · A0AAP9E7H5_RHIRD
- ProteinProtein translocase subunit SecA
- GenesecA
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids905 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
Catalytic activity
Cofactor
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 89 | ATP (UniProtKB | ChEBI) | |||
Binding site | 107-111 | ATP (UniProtKB | ChEBI) | |||
Binding site | 502 | ATP (UniProtKB | ChEBI) | |||
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameProtein translocase subunit SecA
- EC number
Gene names
Organism names
- Strains
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Rhizobiaceae > Rhizobium/Agrobacterium group > Agrobacterium > Agrobacterium tumefaciens complex
Accessions
- Primary accessionA0AAP9E7H5
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell inner membrane ; Peripheral membrane protein
Membrane ; Peripheral membrane protein
Note: Distribution is 50-50.
Keywords
- Cellular component
Interaction
Subunit
Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 5-615 | SecA family profile | |||
Domain | 91-249 | Helicase ATP-binding | |||
Domain | 423-623 | Helicase C-terminal | |||
Sequence similarities
Belongs to the SecA family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length905
- Mass (Da)101,892
- Last updated2024-10-02 v1
- ChecksumA1AA9CD9C8AA7C54
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JAVDSW010000002 EMBL· GenBank· DDBJ | MDR6703127.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP042275 EMBL· GenBank· DDBJ | QDY96091.1 EMBL· GenBank· DDBJ | Genomic DNA |