A0AAP2G7M6 · A0AAP2G7M6_9GAMM

  • Protein
    3-ketoacyl-CoA thiolase
  • Gene
    fadA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.

Catalytic activity

Pathway

Lipid metabolism; fatty acid beta-oxidation.

Features

Showing features for active site.

138750100150200250300350
TypeIDPosition(s)Description
Active site91Acyl-thioester intermediate
Active site343Proton acceptor
Active site373Proton acceptor

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    3-ketoacyl-CoA thiolase
  • EC number
  • Alternative names
    • Acetyl-CoA acyltransferase
    • Beta-ketothiolase
    • Fatty acid oxidation complex subunit beta

Gene names

    • Name
      fadA
    • ORF names
      IAF07_01015
      , JRZ91_01015

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • 16LI01
    • DDI_59W
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Pectobacteriaceae > Dickeya

Accessions

  • Primary accession
    A0AAP2G7M6

Proteomes

Subcellular Location

Cytoplasm

Keywords

Interaction

Subunit

Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain5-254Thiolase N-terminal
Domain262-386Thiolase C-terminal

Sequence similarities

Belongs to the thiolase-like superfamily. Thiolase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    387
  • Mass (Da)
    40,656
  • Last updated
    2024-10-02 v1
  • Checksum
    513EEEE882E2A713
MENAVIVDAVRTPMGRSKGGAFRQVRAETLSAHLMRSLLSRHPALEADKIDDIYWGCVQQTLEQGFNVARNAALLAEIPHSVPAVTVNRLCGSSMQALHDAARAIMVGDAGVCLVGGVEHMGHVPMTHGVDFHPGLGKSIAKAAVMMGLTAELLARRHHISREMQDAFAARSHQRAWAATQSGAFRREIIPTNGHNADGALQPFDYDEVVRAETSIDALAALRPAFDPANGTVTAGSSSALSDGAAALLVMSESRALALGLTPRVRIRAMAVVGCDPSVMGYGPVPATHKALQRAGLSLSDIGLFELNEAFAAQALPCIKALGLMDSLDDKVNLNGGAIALGHPLGCSGARLTATLINLMEQRNVEFGVATMCIGLGQGIATVLERV

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAHEPW010000002
EMBL· GenBank· DDBJ
MBT1486996.1
EMBL· GenBank· DDBJ
Genomic DNA
CP069603
EMBL· GenBank· DDBJ
QVH72005.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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