A0AAP2G7M6 · A0AAP2G7M6_9GAMM
- Protein3-ketoacyl-CoA thiolase
- GenefadA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids387 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
Catalytic activity
- an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA
Pathway
Lipid metabolism; fatty acid beta-oxidation.
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 91 | Acyl-thioester intermediate | |||
Active site | 343 | Proton acceptor | |||
Active site | 373 | Proton acceptor | |||
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name3-ketoacyl-CoA thiolase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strains
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Pectobacteriaceae > Dickeya
Accessions
- Primary accessionA0AAP2G7M6
Proteomes
Subcellular Location
Interaction
Subunit
Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 5-254 | Thiolase N-terminal | |||
Domain | 262-386 | Thiolase C-terminal | |||
Sequence similarities
Belongs to the thiolase-like superfamily. Thiolase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length387
- Mass (Da)40,656
- Last updated2024-10-02 v1
- Checksum513EEEE882E2A713
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JAHEPW010000002 EMBL· GenBank· DDBJ | MBT1486996.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP069603 EMBL· GenBank· DDBJ | QVH72005.1 EMBL· GenBank· DDBJ | Genomic DNA |