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A0AAP0W526 · A0AAP0W526_9GAMM

Function

function

Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-2-decenoyl-ACP and then its isomerization to Z-3-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Lipid metabolism; fatty acid biosynthesis.

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site71

GO annotations

AspectTerm
Molecular Functionlyase activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase
  • EC number
  • Alternative names
    • 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA
    • Beta-hydroxydecanoyl thioester dehydrase
    • Trans-2-decenoyl-[acyl-carrier-protein] isomerase
      (EC:5.3.3.14
      ) . EC:5.3.3.14 (UniProtKB | ENZYME | Rhea)

Gene names

    • Name
      fabA
    • ORF names
      AI28_21030

Organism names

Accessions

  • Primary accession
    A0AAP0W526

Proteomes

Subcellular Location

Cytoplasm

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Belongs to the thioester dehydratase family. FabA subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    172
  • Mass (Da)
    18,798
  • Last updated
    2024-10-02 v1
  • MD5 Checksum
    A3A639C3631D0B5EC8A919ACB9B24B58
MVDKRDSYTKEDLIASGRGELFGAEGPPLPSGNMLMMDRVVKMSEDGGNYGKGFVEAELDINPDLWFFSCHFIGDPVMPGCLGLDAMWQLVGFYLGWLGAEGKGRALGVGEVKFTGQVLPSAKKVSYRIHFKRVINRKLVMGVADGEVLVDGHVIYTATDLKVGLFKDTTAF

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JMSO01000144
EMBL· GenBank· DDBJ
KMV69925.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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