A0AAN9D5C4 · A0AAN9D5C4_9TELE
- ProteinDihydropyrimidine dehydrogenase [NADP(+)]
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1025 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine.
Catalytic activity
- 5,6-dihydrothymine + NADP+ = thymine + NADPH + H+This reaction proceeds in the backward direction.
Cofactor
Protein has several cofactor binding sites:
Note: Binds 4 [4Fe-4S] clusters. Contains approximately 16 iron atoms per subunit.
Pathway
Amino-acid biosynthesis; beta-alanine biosynthesis.
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDihydropyrimidine dehydrogenase [NADP(+)]
- EC number
- Short namesDHPDHase ; DPD
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Leuciscidae > Phoxininae > Phoxinus
Accessions
- Primary accessionA0AAN9D5C4
Proteomes
Structure
Family & Domains
Sequence
- Sequence statusComplete
- Length1,025
- Mass (Da)111,523
- Last updated2024-10-02 v1
- MD5 Checksum9A73BF9DBDC1F2F6311B63C96F74CA12
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JAYKXH010000007 EMBL· GenBank· DDBJ | KAK7162871.1 EMBL· GenBank· DDBJ | Genomic DNA |