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A0AAN9D5C4 · A0AAN9D5C4_9TELE

Function

function

Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
FAD (UniProtKB | Rhea| CHEBI:57692 )

FMN (UniProtKB | Rhea| CHEBI:58210 )

[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

Note: Binds 4 [4Fe-4S] clusters. Contains approximately 16 iron atoms per subunit.

Pathway

Amino-acid biosynthesis; beta-alanine biosynthesis.

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Dihydropyrimidine dehydrogenase [NADP(+)]
  • EC number
  • Short names
    DHPDHase
    ; DPD
  • Alternative names
    • Dihydrothymine dehydrogenase
    • Dihydrouracil dehydrogenase

Gene names

    • ORF names
      R3I93_007039

Organism names

  • Taxonomic identifier
  • Strain
    • ZFMK-TIS-60720
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Leuciscidae > Phoxininae > Phoxinus

Accessions

  • Primary accession
    A0AAN9D5C4

Proteomes

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain946-9784Fe-4S ferredoxin-type
Domain979-10094Fe-4S ferredoxin-type

Sequence similarities

Belongs to the dihydropyrimidine dehydrogenase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,025
  • Mass (Da)
    111,523
  • Last updated
    2024-10-02 v1
  • MD5 Checksum
    9A73BF9DBDC1F2F6311B63C96F74CA12
MATKLSKELPDIESILALNPRVKTYANLHSTASKKNEKKHWKRNQERSCDSCVNLENNFDDIKHTTLSERGALREALRCLKCADAPCQKSCPTNLDIKSFITSISNKNYYGAAKAILSDNPLGLTCGMVCPTSDLCVGGCNLYASEEGPINIGGLQQFATEVFSNMGIPQIRNPELPPAKEMPESYHTRIALIGCGPASISCASFLARLGYDNITIFEKQKYIGGLSTAEIPQFRLPYEVVQFEIDLMKDLGVKVVLDKGLGQNGMTLTSLKEEGFQVIFVGIGLPQANRDTIFEDLTPEKGFYTSKDFLPLVAKASKIGMCNCRSQLPKIHGNVIVLGAGDTAFDCATSALRCGARRVFVVFRKGFTNIRAVPEEMEVAKEEKCEFLPFLSPCEVIKKDGYVVGLRFCRTEQRDDGTWIVDEEQIVHLKADFIISAFGSILNDPAVKKALEPVKLNGWGTPKVNHETMQTSEPWVFAGGDIAGLANTTVESVNDGKQASWHIHKYIQSLHGNTVSTTPKLPLFHCGIDTVDISVEMCGIKFPNPFGLASAPPTTSAAMIRRAFEQGWGFALTKTFGLDKDLVTNVSPRIVRGTTSGHLFGPGQGSFLNIELISEKTAAYWCKSVAELKADFPKNIIIASIMCGYNQADWTELAKMAEDSNADALELNLSCPHGMGERGMGLACGQDTELVRNICRWVRRATTIPFFAKLTPNVTNIVDIARAAYEGGADGVTATNTVSGLMGLKADATPWPGIGRGARTTYGGVSGNAIRPIALRAVSAIARALPGFPILATGGIDSAESGLQFLHTGASVLQVCSAVQNQDFTVIEDYCLGLKALLYLKSIEELHDWDGQSPPTIRHQKGKPVPRVEELVGKSLPSFGPYLQMKTQALVKYKKSLKDASGDVIIDTSDARVNIPKTHVPSVKDVIARALKHIGAYQELDNVEQVQALVDPEMCINCGKCYMTCNDSGYQAIKFDPETHLPVIMDSCTGCTLCLSVCPIIDCIKMVTRTTPYVPKRGLPVNPIC

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAYKXH010000007
EMBL· GenBank· DDBJ
KAK7162871.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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