A0AAN8LDI2 · A0AAN8LDI2_9TELE

  • Protein
    Hedgehog protein
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Protein hedgehog N-product

The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

Protein hedgehog

The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Hedgehog protein

Gene names

    • ORF names
      J4Q44_G00217010

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Cs_M1
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Protacanthopterygii > Salmoniformes > Salmonidae > Coregoninae > Coregonus

Accessions

  • Primary accession
    A0AAN8LDI2

Proteomes

Subcellular Location

Sonic hedgehog protein

Endoplasmic reticulum membrane
Golgi apparatus membrane

Protein hedgehog N-product

Cell membrane
; Lipid-anchor

Keywords

PTM/Processing

Features

Showing features for signal, chain.

Type
IDPosition(s)Description
Signal1-27
ChainPRO_504296298428-476Hedgehog protein

Keywords

Interaction

Subunit

Multimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain200-306Hint
Domain308-352Hint

Sequence similarities

Belongs to the hedgehog family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    476
  • Mass (Da)
    53,234
  • Last updated
    2024-10-02 v1
  • Checksum
    DC14552D1659DC30
MKVSSWWESLARLGLLAIFTWSSLVQGCGPGPGYGNRPRPRKLTPMPYKTSFPKLSENNLGASGRVEGKITRNSERFNELVCNYNTDIIFKDEEKTLADRFMTKRCKDCLNKLAIAVMNHWPGTKLRVTEAWDEDGHHPPDSLHYEGRAVDITTSDRIPDKYGMLAQLAVEAGFDFVYYESKYHVHCSVKADHSVTVEKGGCFPGWARVTLAGGEQKTLASLEPGDRVLALSGSGHIVLSRVLLFLHQDHESRSTFLVLATKDGRRLALTPHHLVFLAPQYKLHHSEYQAQFASRAKPGDYVLIHGADGRVQPSRISSVSQEEGMGVYAPLTEHGTLFVGGVLASSYALIEDHRLAHWAFGPLRLLLSFTQLVRGEGTLGAQVTEAEREHTKTPTHCNTQQKSLRVCVNQTLRSPGVYMNTNTSDRQSSWAAVPINRDIEGGHCDSVQEKVLSVHWYARLLHRLGQFFLDPKTFHH

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAGTTL010000019
EMBL· GenBank· DDBJ
KAK6308430.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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