A0AAN4BIW6 · A0AAN4BIW6_LACRH
- ProteinCardiolipin synthase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids489 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
Catalytic activity
- 2 a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) = a cardiolipin + glycerol
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 222 | ||||
Active site | 224 | ||||
Active site | 229 | ||||
Active site | 407 | ||||
Active site | 409 | ||||
Active site | 414 | ||||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | transferase activity |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCardiolipin synthase
- EC number
- Short namesCL synthase
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Lactobacillales > Lactobacillaceae > Lacticaseibacillus
Accessions
- Primary accessionA0AAN4BIW6
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 34-54 | Helical | |||
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 217-244 | PLD phosphodiesterase | |||
Domain | 402-429 | PLD phosphodiesterase | |||
Sequence similarities
Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length489
- Mass (Da)55,648
- Last updated2024-10-02 v1
- MD5 Checksum5762DCD15668F8C0A7773AC6A0B130DD
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AMQW01000016 EMBL· GenBank· DDBJ | EKS49443.1 EMBL· GenBank· DDBJ | Genomic DNA |