A0AAN3XB45 · A0AAN3XB45_LACRH
- ProteinTranscription-repair-coupling factor
- Genemfd
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1175 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameTranscription-repair-coupling factor
- EC number
- Short namesTRCF
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Lactobacillales > Lactobacillaceae > Lacticaseibacillus
Accessions
- Primary accessionA0AAN3XB45
Proteomes
Subcellular Location
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 633-794 | Helicase ATP-binding | |||
Domain | 815-969 | Helicase C-terminal | |||
Sequence similarities
In the C-terminal section; belongs to the helicase family. RecG subfamily.
In the N-terminal section; belongs to the UvrB family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,175
- Mass (Da)131,925
- Last updated2024-10-02 v1
- Checksum81BEFE41ADCC8E5B
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AMQW01000022 EMBL· GenBank· DDBJ | EKS48904.1 EMBL· GenBank· DDBJ | Genomic DNA |