Essential maintenance is planned to begin on Fri Jan 24 2025. The website may be temporarily unavailable. Please use our fallback: https://wwwdev.ebi.ac.uk/uniprot/front-end/fallback/ in case of any outage.

A0AAN1Q296 · A0AAN1Q296_9LACO

Function

function

Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Note: Mg2+. Can also accept Mn2+.

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2.

Features

Showing features for binding site, active site, site.

Type
IDPosition(s)Description
Binding site8Mg2+ (UniProtKB | ChEBI)
Binding site15ATP (UniProtKB | ChEBI)
Binding site90substrate
Active site147Proton donor/acceptor
Site179Transition state stabilizer
Binding site207-211ATP (UniProtKB | ChEBI)
Site240Transition state stabilizer
Binding site382Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionkinase activity
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Acetate kinase
  • EC number
  • Alternative names
    • Acetokinase

Gene names

    • Name
      ackA
    • ORF names
      LPA65_09100

Organism names

Accessions

  • Primary accession
    A0AAN1Q296

Proteomes

Subcellular Location

Cytoplasm

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Belongs to the acetokinase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    397
  • Mass (Da)
    43,343
  • Last updated
    2024-10-02 v1
  • MD5 Checksum
    A75C283B2499963B467569858FF6439C
MGKTIAINAGSSTLKFKLFEMPQERVIAQGAVERIGFKTSPVNIRYGVDHLYQETAIVADHLTAVNIVLDELIKLRIIDSYDEITGVGHRVVAGGEQFHDSVLITDQVLKQITDLAEYAPLHNPANAVGIRAFKRVLPHVPAVAVFDTAFHASMPAVNYLYSLPYEYYQRYGARKFGAHGTSHRYVAARAAKLLNRPLNALKLITLHLGAGSSITAIDHGQSLDTSMGFTPLAGITMATRSGDVDPSLVVYLMKKLNISDPDEMLAILNTQSGLLGLAGSADMQELEARCDEDPQAQLAIDIFVNRIVKYVGAYLAELQGADALVITAGIGERDARMRQRIADRLTYFGVAIDPNKNQVSGVERDLSTTDAKIRTLLIPTDEELMIARDVERVAASQ

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP032751
EMBL· GenBank· DDBJ
AYJ35907.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help