A0AAN1EE35 · A0AAN1EE35_MYCSY
- ProteinGlycerol-3-phosphate dehydrogenase [NAD(P)+]
- GenegpsA
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids330 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the reduction of the glycolytic intermediate dihydroxyacetone phosphate (DHAP) to sn-glycerol 3-phosphate (G3P), the key precursor for phospholipid synthesis.
Catalytic activity
- sn-glycerol 3-phosphate + NAD+ = dihydroxyacetone phosphate + NADH + H+
Pathway
Membrane lipid metabolism; glycerophospholipid metabolism.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 105 | NADPH (UniProtKB | ChEBI) | |||
Binding site | 105 | sn-glycerol 3-phosphate (UniProtKB | ChEBI) | |||
Binding site | 137 | sn-glycerol 3-phosphate (UniProtKB | ChEBI) | |||
Binding site | 139 | sn-glycerol 3-phosphate (UniProtKB | ChEBI) | |||
Binding site | 141 | NADPH (UniProtKB | ChEBI) | |||
Active site | 192 | Proton acceptor | |||
Binding site | 192 | sn-glycerol 3-phosphate (UniProtKB | ChEBI) | |||
Binding site | 245 | sn-glycerol 3-phosphate (UniProtKB | ChEBI) | |||
Binding site | 255 | sn-glycerol 3-phosphate (UniProtKB | ChEBI) | |||
Binding site | 256 | NADPH (UniProtKB | ChEBI) | |||
Binding site | 256 | sn-glycerol 3-phosphate (UniProtKB | ChEBI) | |||
Binding site | 257 | sn-glycerol 3-phosphate (UniProtKB | ChEBI) | |||
Binding site | 279 | NADPH (UniProtKB | ChEBI) | |||
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGlycerol-3-phosphate dehydrogenase [NAD(P)+]
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Mycoplasmatota > Mycoplasmoidales > Metamycoplasmataceae > Mycoplasmopsis
Accessions
- Primary accessionA0AAN1EE35
Proteomes
Subcellular Location
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 3-161 | Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal | |||
Domain | 181-319 | Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal | |||
Sequence similarities
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length330
- Mass (Da)36,402
- Last updated2024-10-02 v1
- ChecksumC5C3F872620C7FEE
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP107525 EMBL· GenBank· DDBJ | UZW64430.1 EMBL· GenBank· DDBJ | Genomic DNA |