A0AAN1B2V6 · A0AAN1B2V6_MYCSY
- ProteinDNA ligase
- GeneligA
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids697 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
Catalytic activity
Cofactor
Mn2+ (UniProtKB | Rhea| CHEBI:29035 )
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 34-38 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 83-84 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 114 | NAD+ (UniProtKB | ChEBI) | |||
Active site | 116 | N6-AMP-lysine intermediate | |||
Binding site | 137 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 171 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 315 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 339 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 430 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 433 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 448 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 453 | Zn2+ (UniProtKB | ChEBI) | |||
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDNA ligase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Mycoplasmatota > Mycoplasmoidales > Metamycoplasmataceae > Mycoplasmopsis
Accessions
- Primary accessionA0AAN1B2V6
Proteomes
Structure
Sequence
- Sequence statusComplete
- Length697
- Mass (Da)80,491
- Last updated2024-10-02 v1
- Checksum1CA9EC2F644429E6
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP107525 EMBL· GenBank· DDBJ | UZW64331.1 EMBL· GenBank· DDBJ | Genomic DNA |