A0AAN0VC87 · A0AAN0VC87_9PSED

Function

function

Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.

Catalytic activity

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Chaperone SurA
  • Alternative names
    • Peptidyl-prolyl cis-trans isomerase SurA
      (PPIase SurA
      ) (EC:5.2.1.8
      ) . EC:5.2.1.8 (UniProtKB | ENZYME | Rhea)
    • Rotamase SurA

Gene names

    • Name
      surA
    • ORF names
      PVLB_23190

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • VLB120
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas

Accessions

  • Primary accession
    A0AAN0VC87

Proteomes

Subcellular Location

Periplasm
Note: Is capable of associating with the outer membrane.

Keywords

PTM/Processing

Features

Showing features for signal, chain.

Type
IDPosition(s)Description
Signal1-25
ChainPRO_504265056826-439Chaperone SurA

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain176-277PpiC
Domain287-386PpiC

Domain

The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    439
  • Mass (Da)
    49,074
  • Last updated
    2024-10-02 v1
  • Checksum
    A1910941AD65427A
MKTKLIDRLRPLLVGAALLSSAVHAAVQPLDRVVAIVDNDVVMQSQLDQRVHEVQQTIAKRGGGVPPTGALEQQVLERLIVENLQLQIGERSGIRITDEELNQAIGTIAQRNGMSLDQFRAALAHDGLSFDDAREQVKREMIISRVRQRRVAERIQVSEQEVKNFLASDLGKMQMSEEYRLANILIPTPEGANSQDIQNAARKVGDVYQQLRQGADFGQMAIANSASENALEGGEMGWRKAGQLPPEFAKLLSTMSTGDITQPLRIPSGFIIIKLEEKRGGSENVLRDEVHVRHILIKPSEIRSEAATEQLAERLYERIKNGEDFGELAKSFSEDPGSALNGGDLNWVDPNSLVPEFREQMANAQQGVVTKPFKTQYGWHVLEVLGRRATDSTEQAREMQAMNVLRNRKYDEELQTWLRQIRDEAYVEIKLPGADQATQ

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP003961
EMBL· GenBank· DDBJ
AGZ37417.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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