A0AAJ8WQD4 · A0AAJ8WQD4_SALET

Function

function

Catalyzes the decarboxylation of 3-keto-L-gulonate-6-P into L-xylulose-5-P. Is involved in the anaerobic L-ascorbate utilization.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 1 Mg2+ ion per subunit.

Pathway

Cofactor degradation; L-ascorbate degradation; D-xylulose 5-phosphate from L-ascorbate: step 2/4.

Features

Showing features for binding site, site.

Type
IDPosition(s)Description
Binding site11substrate
Binding site33Mg2+ (UniProtKB | ChEBI)
Binding site62Mg2+ (UniProtKB | ChEBI)
Site64Transition state stabilizer
Site67Transition state stabilizer
Binding site192substrate

GO annotations

AspectTerm
Molecular Function3-dehydro-L-gulonate-6-phosphate decarboxylase activity
Molecular Functionmagnesium ion binding
Molecular Functionorotidine-5'-phosphate decarboxylase activity
Biological Process'de novo' pyrimidine nucleobase biosynthetic process
Biological ProcessL-ascorbic acid catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    3-keto-L-gulonate-6-phosphate decarboxylase UlaD
  • EC number
  • Alternative names
    • 3-dehydro-L-gulonate-6-phosphate decarboxylase
    • KGPDC
    • L-ascorbate utilization protein D

Gene names

    • Name
      ulad
    • Synonyms
      ulaD
    • ORF names
      SCA50_4555

Organism names

Accessions

  • Primary accession
    A0AAJ8WQD4

Proteomes

Expression

Induction

Induced by L-ascorbate. Repressed by UlaR.

Interaction

Subunit

Homodimer.

Structure

3D structure databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain5-207Orotidine 5'-phosphate decarboxylase

Sequence similarities

Belongs to the HPS/KGPDC family. KGPDC subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    216
  • Mass (Da)
    23,706
  • Last updated
    2024-07-24 v1
  • Checksum
    CDF280DC1D1BAD68
MSLPMLQVALDNQTMDSAYETTRLIAEEVDIIEVGTILCVGEGVRAVRDLKALYPHKIVLADAKIADAGKILSRMCFEANADWVTVICCADINTAKGALDVAKEFNGDVQIELTGYWTWEQAQQWRDAGIQQVVYHRSRDAQAAGVAWGEADITAIKRLSDMGFKVTVTGGLALEDLPLFKGIPIHVFIAGRSIRDAESPVEAARQFKRSIAQLWG

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CM001062
EMBL· GenBank· DDBJ
EFZ08903.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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