A0AAJ8WQD4 · A0AAJ8WQD4_SALET
- Protein3-keto-L-gulonate-6-phosphate decarboxylase UlaD
- Geneulad
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids216 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
function
Catalyzes the decarboxylation of 3-keto-L-gulonate-6-P into L-xylulose-5-P. Is involved in the anaerobic L-ascorbate utilization.
Catalytic activity
- 3-dehydro-L-gulonate 6-phosphate + H+ = L-xylulose 5-phosphate + CO2
Cofactor
Note: Binds 1 Mg2+ ion per subunit.
Pathway
Cofactor degradation; L-ascorbate degradation; D-xylulose 5-phosphate from L-ascorbate: step 2/4.
Features
Showing features for binding site, site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 11 | substrate | |||
Binding site | 33 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 62 | Mg2+ (UniProtKB | ChEBI) | |||
Site | 64 | Transition state stabilizer | |||
Site | 67 | Transition state stabilizer | |||
Binding site | 192 | substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 3-dehydro-L-gulonate-6-phosphate decarboxylase activity | |
Molecular Function | magnesium ion binding | |
Molecular Function | orotidine-5'-phosphate decarboxylase activity | |
Biological Process | 'de novo' pyrimidine nucleobase biosynthetic process | |
Biological Process | L-ascorbic acid catabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name3-keto-L-gulonate-6-phosphate decarboxylase UlaD
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Salmonella
Accessions
- Primary accessionA0AAJ8WQD4
Proteomes
Expression
Induction
Induced by L-ascorbate. Repressed by UlaR.
Interaction
Subunit
Homodimer.
Sequence
- Sequence statusComplete
- Length216
- Mass (Da)23,706
- Last updated2024-07-24 v1
- ChecksumCDF280DC1D1BAD68
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CM001062 EMBL· GenBank· DDBJ | EFZ08903.1 EMBL· GenBank· DDBJ | Genomic DNA |