A0AAJ7XJU4 · A0AAJ7XJU4_PETMA

Function

function

Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.

Names & Taxonomy

Protein names

  • Recommended name
    Zona pellucida sperm-binding protein 3

Gene names

    • Name
      LOC116958493

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Cyclostomata > Hyperoartia > Petromyzontiformes > Petromyzontidae > Petromyzon

Accessions

  • Primary accession
    A0AAJ7XJU4

Proteomes

Subcellular Location

Zona pellucida
Cell membrane
; Single-pass type I membrane protein

Keywords

PTM/Processing

Post-translational modification

Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-291ZP

Domain

The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.

Sequence similarities

Belongs to the ZP domain family. ZPC subfamily.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    367
  • Mass (Da)
    40,156
  • Last updated
    2024-07-24 v1
  • Checksum
    00FC1D17A2A85C6D
MSPRADKSHESGRELRWLCWCRAKSRFFAVLAMETTRALFAVLELLCLASATVATSATVSVVCDEATLTLTVSRDLFGTGHLAQASDLSLGVPACPVTGSDALAGTVTFLYALESCGTSLQMSAGLLSYENYLYYRPTSNTGIIRTNYVAVPVVCLYPRRVHQQSLIYQLGQTLNVEASVQTLNHVPLRIFVVSCFATPVPDRNAPLCYQIISNSGCLVDGKVSYDAHLTSGFLLRQSDNVLRFFIDSFRFLATLTNNGDQVFVFCQLKVADVATSPTTVKKACTYSPSAAYRWISADGLDSVCSCCEATCPSGRKRRDVAAVTGEYNRRNQPFSLIQKTLEYQGSYVLGNCQKSQTATYTMQTLPK

Sequence databases

Similar Proteins

Disclaimer

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