A0AAJ4E205 · A0AAJ4E205_9GAMM

  • Protein
    Dissimilatory sulfite reductase
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Respiratory sulfite reductase that catalyzes the reduction of sulfite to sulfide in a single step, consuming six electrons in the process.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Cu+ (UniProtKB | Rhea| CHEBI:49552 )

Note: Exposure to oxygen reduces copper binding and leads to the formation of a disulfide bond between the two Cys residues that bind the copper ion.
heme c (UniProtKB | Rhea| CHEBI:61717 )

Note: Binds 8 heme c groups covalently per monomer.

Pathway

Sulfur metabolism; sulfite reduction.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site141heme c 1 (UniProtKB | ChEBI); covalent
Binding site144heme c 1 (UniProtKB | ChEBI); covalent
Binding site145Fe (UniProtKB | ChEBI) of heme c 1 (UniProtKB | ChEBI); axial binding residue
Binding site157Fe (UniProtKB | ChEBI) of heme c 4 (UniProtKB | ChEBI); axial binding residue
Binding site208substrate
Binding site285substrate
Binding site302heme c 2 (UniProtKB | ChEBI); covalent
Binding site305heme c 2 (UniProtKB | ChEBI); covalent
Binding site306Fe (UniProtKB | ChEBI) of heme c 2 (UniProtKB | ChEBI); axial binding residue
Binding site339heme c 3 (UniProtKB | ChEBI); covalent
Binding site342heme c 3 (UniProtKB | ChEBI); covalent
Binding site343Fe (UniProtKB | ChEBI) of heme c 3 (UniProtKB | ChEBI); axial binding residue
Binding site348Fe (UniProtKB | ChEBI) of heme c 1 (UniProtKB | ChEBI); axial binding residue
Binding site360heme c 4 (UniProtKB | ChEBI); covalent
Binding site363heme c 4 (UniProtKB | ChEBI); covalent
Binding site364Fe (UniProtKB | ChEBI) of heme c 4 (UniProtKB | ChEBI); axial binding residue
Binding site366substrate
Binding site398Cu+ (UniProtKB | ChEBI)
Binding site410Fe (UniProtKB | ChEBI) of heme c 6 (UniProtKB | ChEBI); axial binding residue
Binding site417heme c 5 (UniProtKB | ChEBI); covalent
Binding site420heme c 5 (UniProtKB | ChEBI); covalent
Binding site421Fe (UniProtKB | ChEBI) of heme c 5 (UniProtKB | ChEBI); axial binding residue
Binding site424Fe (UniProtKB | ChEBI) of heme c 3 (UniProtKB | ChEBI); axial binding residue
Binding site444heme c 6 (UniProtKB | ChEBI); covalent
Binding site447heme c 6 (UniProtKB | ChEBI); covalent
Binding site448Fe (UniProtKB | ChEBI) of heme c 6 (UniProtKB | ChEBI); axial binding residue
Binding site461Fe (UniProtKB | ChEBI) of heme c 8 (UniProtKB | ChEBI); axial binding residue
Binding site466heme c 7 (UniProtKB | ChEBI); covalent
Binding site469heme c 7 (UniProtKB | ChEBI); covalent
Binding site470Fe (UniProtKB | ChEBI) of heme c 7 (UniProtKB | ChEBI); axial binding residue
Binding site477Cu+ (UniProtKB | ChEBI)
Binding site498Fe (UniProtKB | ChEBI) of heme c 5 (UniProtKB | ChEBI); axial binding residue
Binding site544heme c 8 (UniProtKB | ChEBI); covalent
Binding site560heme c 8 (UniProtKB | ChEBI); covalent
Binding site561Fe (UniProtKB | ChEBI) of heme c 8 (UniProtKB | ChEBI); axial binding residue
Binding site645Fe (UniProtKB | ChEBI) of heme c 7 (UniProtKB | ChEBI); axial binding residue

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Dissimilatory sulfite reductase
  • EC number

Gene names

    • ORF names
      FS418_24530

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • YLB-09
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Alteromonadales > Shewanellaceae > Shewanella

Accessions

  • Primary accession
    A0AAJ4E205

Proteomes

Subcellular Location

Periplasm

Keywords

PTM/Processing

Features

Showing features for signal, chain.

TypeIDPosition(s)Description
Signal1-24
ChainPRO_504230374825-678Dissimilatory sulfite reductase

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain140-162Cytochrome c-552/4

Sequence similarities

Belongs to the multiheme cytochrome c family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    678
  • Mass (Da)
    75,906
  • Last updated
    2024-07-24 v1
  • Checksum
    8327B2BEB5244DF3
MKNWKLKAVASVLFCFGAVSNVSAAGGKYNSIPEMGESAKNSIANYTGTEETKGVKSLQDYIVQEDELFDFLFNNHPMFKYHEDGNLIGEYHISDRGEEYLDTGNSPKYSARVGRPSAVQYRLGAKSTLDFPNNFVGPEKCAECHAVQYEKWQRSRHANVVRFPSEITDKEVPNGDLNAKLYGSEAAMLPDGIRANDVYAIIGTPRTKYGFLDSYLVRGTYHIRDGLLSEGTGKMVAGANQFSRGWAEWLTPEMAKKINKVIPEFPTTIEDFGDSGSHQWGMSSYGAKYEKELLFQPASSYCEMCHTFKFDFQSKEEYFAALGDSKKLQEHTISKGISCEECHGAGGHLDGGTGGMQSNCERCHQRFNFVDELADTEKGQEKMEYAFGVKMKSACPSCGTEGSQMFASAHYEKGMRCTTCHDPHEVTDGDFLSGFTKPLLKKQCVDCHEVQATIAENTDTHSKQTCQSCHMPAMGSCENFTATQFPDMAGFDAVRKSHMWKIDIHPERKTLNPPTGQPRDAAVKGWTVAKNEEDHNYLDLMWSCARTAVSDHDNVENKGCHSPFQSELETGLHYEDQLEIYGEVMKWQNPVKQVFADVEQALERIDQLLEVTKLSIEDKTQVLMLAEKAQETVDFIRKDGSWGVHGFRYSQKRLDAALTYVTQAQKILDGTGYSAKSH

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP045427
EMBL· GenBank· DDBJ
QFU25470.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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