A0AAJ2VP42 · A0AAJ2VP42_9GAMM

  • Protein
    3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase
  • Gene
    fabA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-2-decenoyl-ACP and then its isomerization to Z-3-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Lipid metabolism; fatty acid biosynthesis.

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site70

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Function(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
Molecular Functiontrans-2-decenoyl-acyl-carrier-protein isomerase activity
Biological Processunsaturated fatty acid biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase
  • EC number
  • Alternative names
    • 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA
    • Beta-hydroxydecanoyl thioester dehydrase
    • Trans-2-decenoyl-[acyl-carrier-protein] isomerase
      (EC:5.3.3.14
      ) . EC:5.3.3.14 (UniProtKB | ENZYME | Rhea)

Gene names

    • Name
      fabA
    • ORF names
      SIL78_11180

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • ATCC BAA-953
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Oceanospirillales > Halomonadaceae > Vreelandella

Accessions

  • Primary accession
    A0AAJ2VP42

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Belongs to the thioester dehydratase family. FabA subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    171
  • Mass (Da)
    18,876
  • Last updated
    2024-07-24 v1
  • Checksum
    2FEC75E180C6CB90
MTKQHSFDREELLACSRGELFGPGNAQLPAPNMLMLDRIMHIHEEGGVHGKGELIAELDITPDLWFFDCHFPGDPVMPGCLGLDAMWQLVGFYLGWLGHPGRGRALGCGDVKFSGQILPDAKKVTYHINVKRIITRRLILGIADGTVSVDGRDIYQANDLRVGLFTSTANF

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAWXXT010000001
EMBL· GenBank· DDBJ
MDX5978132.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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