A0AAJ2T361 · A0AAJ2T361_9STRE

Function

function

Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 3/7.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site63-dehydroquinate (UniProtKB | ChEBI)
Binding site30-323-dehydroquinate (UniProtKB | ChEBI)
Binding site623-dehydroquinate (UniProtKB | ChEBI)
Active site118Proton donor/acceptor
Active site143Schiff-base intermediate with substrate
Binding site1863-dehydroquinate (UniProtKB | ChEBI)
Binding site2053-dehydroquinate (UniProtKB | ChEBI)
Binding site2093-dehydroquinate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Function3-dehydroquinate dehydratase activity
Biological Process3,4-dihydroxybenzoate biosynthetic process
Biological Processamino acid biosynthetic process
Biological Processaromatic amino acid family biosynthetic process
Biological Processchorismate biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    3-dehydroquinate dehydratase
  • EC number
  • Short names
    3-dehydroquinase
  • Alternative names
    • Type I DHQase
    • Type I dehydroquinase
      (DHQ1
      )

Gene names

    • Name
      aroD
    • ORF names
      SPD57_06770

Organism names

  • Taxonomic identifier
  • Strain
    • BJSWXB6CM1
  • Taxonomic lineage
    Bacteria > Bacillota > Bacilli > Lactobacillales > Streptococcaceae > Streptococcus

Accessions

  • Primary accession
    A0AAJ2T361

Proteomes

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Belongs to the type-I 3-dehydroquinase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    225
  • Mass (Da)
    25,611
  • Last updated
    2024-07-24 v1
  • Checksum
    F9DFB006FBB1DEF4
MKLVVSVMPKSIEEVQGIDAMRYIDADIIEWRADFLPKEAILQVAPAIFEKFAGRELLFTLRTRAEGGEIDLDSVEYVQIIKDVAQLYQPEYIDFEYFSHKDVFEEMLDFPNLVLSYHNFQETPENMMEILSELTSLTPKVVKVSVMAQTEQDVLDLMNFTRGFKTLNPEQEYVTISMGKVGKVSRITSDVTGSSWSFASLDEASAPGQISLSSMKKIREILNED

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAXHDQ010000007
EMBL· GenBank· DDBJ
MDY4371617.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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