A0AAJ2J7I9 · A0AAJ2J7I9_9GAMM

  • Protein
    Fatty acid oxidation complex subunit alpha
  • Gene
    fadJ
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Lipid metabolism; fatty acid beta-oxidation.

Features

Showing features for site.

TypeIDPosition(s)Description
Site116Important for catalytic activity
Site138Important for catalytic activity

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Fatty acid oxidation complex subunit alpha

Including 2 domains:

  • Recommended name
    Enoyl-CoA hydratase/3-hydroxybutyryl-CoA epimerase
  • EC number
  • Recommended name
    3-hydroxyacyl-CoA dehydrogenase
  • EC number

Gene names

    • Name
      fadJ
    • ORF names
      Q4Q49_15330

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • SP1S1-7
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Alteromonadales > Shewanellaceae > Shewanella

Accessions

  • Primary accession
    A0AAJ2J7I9

Proteomes

Subcellular Location

Cytoplasm

Keywords

Interaction

Subunit

Heterotetramer of two alpha chains (FadJ) and two beta chains (FadI).

Family & Domains

Features

Showing features for region, domain.

TypeIDPosition(s)Description
Region1-188Enoyl-CoA hydratase
Region308-7063-hydroxyacyl-CoA dehydrogenase
Domain313-4913-hydroxyacyl-CoA dehydrogenase NAD binding
Domain494-5873-hydroxyacyl-CoA dehydrogenase C-terminal
Domain618-7023-hydroxyacyl-CoA dehydrogenase C-terminal

Sequence similarities

In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    706
  • Mass (Da)
    75,754
  • Last updated
    2024-07-24 v1
  • Checksum
    9344784ABAA03F53
MEKTFNLTRRDDGIAILTMDVPGETMNTLKAQFGPEISEILAEIKSDSSIRGLVLISGKKDSFVAGADISMLDACKTASDAKALSQQGHVVFNELEALTIPVVAAIHGACLGGGLELALACHQRVCSDDGKTMLGVPEVQLGLLPGGGGTQRLPRLVGITTALDMMLTGKQIRPKQALKMGLVNDVVPQTILLQTAVEMALAGKRVPKPVKKSLVNQVLEGTSFGRNIIFDQATKQVEKKTQGNYPAPAKIIDCVRQGIAKGMQKGLEVEASHFAELVVSKESEALRSIFFATTEMKKETGAEGASPRKVKKAVILGGGLMGGGIASVTTTKAKIPVRVKDISEKGLSNALAYAYKLLDKGVKRRHMTPAARDNLMALMTTTTEYKGVKDADIVVEAVFEDLALKHQMVKDIERECGEHTIFASNTSSLPISQIAEAATRPENVIGLHYFSPVEKMPLVEVIAHAKTSPETIATTVAFARKQGKTPIVVQDGAGFYVNRILALYMNEAAQLLLEGQSVEHLDKALVKFGFPVGPITLLDEVGIDVGAKISPILEKELGERFKAPAAFDKLLGDDRKGRKNGKGFYQYGASSKKAKAVDESVYGVLGIKPGTNKDAKAVAERCVVQMLNEAVRCLDDGIIASPRDGDIGAIFGIGFPPFLGGPFHYIDTLGAANLVRILEGYQSQLGSRFEPCERLKTMAQENAHFF

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAUOEU010000020
EMBL· GenBank· DDBJ
MDT3336658.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp