A0AAJ2I9C0 · A0AAJ2I9C0_9ACTN
- ProteinTryptophan synthase beta chain
- GenetrpB
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids448 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
Catalytic activity
- (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D-glyceraldehyde 3-phosphate + L-tryptophan + H2O
Cofactor
Pathway
Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 5/5.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | tryptophan synthase activity | |
Biological Process | tryptophan metabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameTryptophan synthase beta chain
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Mycobacteriales > Gordoniaceae > Gordonia
Accessions
- Primary accessionA0AAJ2I9C0
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for modified residue.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Modified residue | 118 | N6-(pyridoxal phosphate)lysine | |||
Interaction
Subunit
Tetramer of two alpha and two beta chains.
Structure
Family & Domains
Features
Showing features for region, domain, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 1-30 | Disordered | |||
Domain | 83-408 | Tryptophan synthase beta chain-like PALP | |||
Region | 425-448 | Disordered | |||
Compositional bias | 431-448 | Polar residues | |||
Sequence similarities
Belongs to the TrpB family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length448
- Mass (Da)47,611
- Last updated2024-07-24 v1
- Checksum9ACDBC478D0ED77C
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 431-448 | Polar residues | |||
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JAUZVK010000001 EMBL· GenBank· DDBJ | MDT0219416.1 EMBL· GenBank· DDBJ | Genomic DNA |