A0AAI9J0W1 · A0AAI9J0W1_BORPT

Function

function

Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
K+ (UniProtKB | Rhea| CHEBI:29103 )

NH4+ (UniProtKB | Rhea| CHEBI:28938 )

K+ (UniProtKB | Rhea| CHEBI:29103 )

Note: A monovalent cation. Ammonium or potassium.

Pathway

Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site6-13ATP (UniProtKB | ChEBI)
Binding site96substrate
Binding site103-106substrate
Active site105Proton acceptor
Binding site131ATP (UniProtKB | ChEBI)
Binding site181substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionpantothenate kinase activity
Biological Processcoenzyme A biosynthetic process
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Type III pantothenate kinase
  • EC number
  • Alternative names
    • PanK-III
    • Pantothenic acid kinase

Gene names

    • Name
      coaX
    • ORF names
      L566_3619

Organism names

  • Taxonomic identifier
  • Strain
    • CHLA-26
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Alcaligenaceae > Bordetella

Accessions

  • Primary accession
    A0AAI9J0W1

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Structure

3D structure databases

Family & Domains

Sequence similarities

Belongs to the type III pantothenate kinase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    267
  • Mass (Da)
    27,845
  • Last updated
    2024-07-24 v1
  • Checksum
    336A615F67B57901
MIILIDSGNSRLKVGWFDPDAPQAAREPAPVAFDNLDLDALGRWLATLPRRPQRALGVNVAGLARGEAIAATLRAGGCDIRWLRAQPLAMGLRNGYRNPDQLGADRWACMVGVLARQPSVHPPLLVASFGTATTLDTIGPDNVFPGGLILPGPAMMRGALAYGTAHLPLADGLVADYPIDTHQAIASGIAAAQAGAIVRQWLAGRQRYGQAPEIYVAGGGWPEVRQEAERLLAVTGAAFGATPQPTYLDSPVLDGLAALAAQGAPTA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AXSB02000025
EMBL· GenBank· DDBJ
ETH30617.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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