A0AAI8HS75 · A0AAI8HS75_9BACI

  • Protein
    Protein-arginine kinase
  • Gene
    mcsB
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity.

Catalytic activity

Activity regulation

Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.

Features

Showing features for binding site.

136350100150200250300350
TypeIDPosition(s)Description
Binding site27-31ATP (UniProtKB | ChEBI)
Binding site92ATP (UniProtKB | ChEBI)
Binding site125ATP (UniProtKB | ChEBI)
Binding site176-180ATP (UniProtKB | ChEBI)
Binding site207-212ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular FunctionATP binding
Molecular Functioncreatine kinase activity
Molecular Functionprotein kinase activity
Biological Processphosphocreatine biosynthetic process
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Protein-arginine kinase
  • EC number

Gene names

    • Name
      mcsB
    • ORF names
      CWD84_21400

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • SCSIO 05746
  • Taxonomic lineage
    Bacteria > Bacillota > Bacilli > Bacillales > Bacillaceae > Bacillus > Bacillus amyloliquefaciens group

Accessions

  • Primary accession
    A0AAI8HS75

Proteomes

Family & Domains

Features

Showing features for domain, motif.

Type
IDPosition(s)Description
Domain24-254Phosphagen kinase C-terminal
Motif337-342RDXXRA motif of the pArg binding pocket involved in allosteric regulation

Sequence similarities

Belongs to the ATP:guanido phosphotransferase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    363
  • Mass (Da)
    40,984
  • Last updated
    2024-07-24 v1
  • Checksum
    985C5696223CA8BD
MSLKHFIQDALSNWMKQKGPESDIVLSSRIRLARNFENIKFPARYTNEEASSIIQQFEDHFSGKELPDIGQFHLIRMSEAQPLEKRVLMEKHLISPNLTESPFGGCLLSENEEVSIMLNEEDHIRIQCLFPGFQLLNAIKAANQVDDWIEEKVDYAFGEKRGYLTSCPTNVGTGLRASVMMHLPGLVLTRQMNRIIPAINQLGLVVRGIYGEGSEALGNIFQISNQITLGKSEQDIVDDLNSVAAQLIEQERSAREALYQTSKIELEDRVFRSYGVLSNCRMIESKETAKCLSDVRLGIDLGIIKGLSSNILNELMILTQPGFLQQYSGGALRPNERDARRAALIRERLRLEMSANRQEDDSI

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP025001
EMBL· GenBank· DDBJ
AUJ79163.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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