A0AAE9X0M2 · A0AAE9X0M2_9CAUD
- ProteinNAD--protein ADP-ribosyltransferase modB
- GenemodB
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids207 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
ADP-ribosyltransferase that regulates transcription by ADP-ribosylation of host ribosomal protein S1. Additional identified targets include proteins involved in either translation or cellular metabolism such as elongation factor-Tu or trigger factor. Also reprograms the host's gene-expression system by RNAylating host ribosomal protein S1. ModB can attach NAD-capped RNAs to target proteins post-transcriptionally resulting in covalent RNA-protein conjugates.
Catalytic activity
- L-arginyl-[protein] + NAD+ = N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide + H+
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 73 | NAD+ (UniProtKB | ChEBI) | |||
Active site | 173 | ||||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | virion component | |
Molecular Function | NAD+-protein-arginine ADP-ribosyltransferase activity | |
Molecular Function | nucleotidyltransferase activity |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameNAD--protein ADP-ribosyltransferase modB
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageViruses > Duplodnaviria > Heunggongvirae > Uroviricota > Caudoviricetes > Straboviridae > Tevenvirinae > Tequatrovirus
Accessions
- Primary accessionA0AAE9X0M2
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Note: This protein is injected from the virion into the bacterial cell.
Keywords
- Cellular component
Structure
Family & Domains
Sequence similarities
Belongs to the Tevenvirinae NAD--protein ADP-ribosyltransferase modA family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length207
- Mass (Da)24,333
- Last updated2024-05-29 v1
- Checksum0CD27F8AE2CE7A79
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
OQ174502 EMBL· GenBank· DDBJ | WCA46068.1 EMBL· GenBank· DDBJ | Genomic DNA |