A0AAE9X0M2 · A0AAE9X0M2_9CAUD

  • Protein
    NAD--protein ADP-ribosyltransferase modB
  • Gene
    modB
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

ADP-ribosyltransferase that regulates transcription by ADP-ribosylation of host ribosomal protein S1. Additional identified targets include proteins involved in either translation or cellular metabolism such as elongation factor-Tu or trigger factor. Also reprograms the host's gene-expression system by RNAylating host ribosomal protein S1. ModB can attach NAD-capped RNAs to target proteins post-transcriptionally resulting in covalent RNA-protein conjugates.

Catalytic activity

Features

Showing features for binding site, active site.

120720406080100120140160180200
Type
IDPosition(s)Description
Binding site73NAD+ (UniProtKB | ChEBI)
Active site173

GO annotations

AspectTerm
Cellular Componentvirion component
Molecular FunctionNAD+-protein-arginine ADP-ribosyltransferase activity
Molecular Functionnucleotidyltransferase activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NAD--protein ADP-ribosyltransferase modB
  • EC number

Gene names

    • Name
      modB

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • REP3
  • Taxonomic lineage
    Viruses > Duplodnaviria > Heunggongvirae > Uroviricota > Caudoviricetes > Straboviridae > Tevenvirinae > Tequatrovirus

Accessions

  • Primary accession
    A0AAE9X0M2

Proteomes

Subcellular Location

Virion
Note: This protein is injected from the virion into the bacterial cell.

Keywords

  • Cellular component

Family & Domains

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    207
  • Mass (Da)
    24,333
  • Last updated
    2024-05-29 v1
  • Checksum
    0CD27F8AE2CE7A79
MIINLTDVEQLSIKAESVDFQYDMYKKVCEKFTDFEQSVLWQCMEAKKNEALHRQLNKIVKKHLTKSPYQLYRGISKSTKELIKDLQVGEVFSTNRVDSFTTSLHIACGFSYVEYFTEIIFRLKTDKAFNYSDHISDIILSSPNTEFKYTYEDTDGLDSERTDNLMMIVREQEWMIPIGKYKITSISKEKLHDSFGTFKVYDIEVVE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
OQ174502
EMBL· GenBank· DDBJ
WCA46068.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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