A0AAE9GSV7 · A0AAE9GSV7_9NEIS

  • Protein
    Pyridoxine 5'-phosphate synthase
  • Gene
    pdxJ
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.

Catalytic activity

Pathway

Cofactor biosynthesis; pyridoxine 5'-phosphate biosynthesis; pyridoxine 5'-phosphate from D-erythrose 4-phosphate: step 5/5.

Features

Showing features for binding site, active site, site.

124320406080100120140160180200220240
TypeIDPosition(s)Description
Binding site63-amino-2-oxopropyl phosphate (UniProtKB | ChEBI)
Binding site8-91-deoxy-D-xylulose 5-phosphate (UniProtKB | ChEBI)
Binding site173-amino-2-oxopropyl phosphate (UniProtKB | ChEBI)
Active site42Proton acceptor
Binding site441-deoxy-D-xylulose 5-phosphate (UniProtKB | ChEBI)
Binding site491-deoxy-D-xylulose 5-phosphate (UniProtKB | ChEBI)
Active site69Proton acceptor
Binding site991-deoxy-D-xylulose 5-phosphate (UniProtKB | ChEBI)
Site150Transition state stabilizer
Active site190Proton donor
Binding site1913-amino-2-oxopropyl phosphate (UniProtKB | ChEBI)
Binding site212-2133-amino-2-oxopropyl phosphate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionpyridoxine 5'-phosphate synthase activity
Biological Processpyridoxine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Pyridoxine 5'-phosphate synthase
  • EC number
  • Short names
    PNP synthase

Gene names

    • Name
      pdxJ
    • ORF names
      LVJ78_09735

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • 1258/02
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Betaproteobacteria > Neisseriales > Neisseriaceae > Uruburuella

Accessions

  • Primary accession
    A0AAE9GSV7

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homooctamer; tetramer of dimers.

Family & Domains

Sequence similarities

Belongs to the PNP synthase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    243
  • Mass (Da)
    26,367
  • Last updated
    2024-05-29 v1
  • Checksum
    373DBABB04AA5891
MLLGVNIDHVATLRNARGTPYPSPLEAALIAETHGADLITLHLREDRRHIKDADVFAIKQAIRTRMNLEMALTEEMLENALKVMPADVCIVPEKREEITTEGGLDVLAQQEKIAAFTHTLSQAGIRVSLFIDADEAQIQAAKEVGAPVIELHTGAYADAATPSERAQQLARIENGAHFGSESGLVVNAGHGLTIHNVSPVAKILAIHELNIGHSLMAQALFLGLPEAIRQMKDVMFKARALPY

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP091507
EMBL· GenBank· DDBJ
UOO78967.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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