A0AAE9DJF8 · A0AAE9DJF8_CAEBR
- Proteinphenylalanine 4-monooxygenase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids474 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-phenylalanine + O2 = (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tyrosine
Cofactor
Pathway
Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 1/6.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | iron ion binding | |
Molecular Function | phenylalanine 4-monooxygenase activity | |
Biological Process | L-phenylalanine catabolic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namephenylalanine 4-monooxygenase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Nematoda > Chromadorea > Rhabditida > Rhabditina > Rhabditomorpha > Rhabditoidea > Rhabditidae > Peloderinae > Caenorhabditis
Accessions
- Primary accessionA0AAE9DJF8
Proteomes
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 31-108 | ACT | ||||
Sequence: TIVFTLREKAGALAETLKLFQAHDVNLSHIESRPSKTHQGCYEVLVEFAEAEDHHKIEGVIEHFQQKAVQKVLVQDWN | ||||||
Domain | 122-468 | Biopterin-dependent aromatic amino acid hydroxylase family profile | ||||
Sequence: VIRWLANVFIDSVPWFPQKISDIDQFANRILSYGAELDCDHPGFKDQTYRERRKFFADIAFNFKHGDKIPTIDYTPEEIATWRTVYNELTVLYPKNACQEFNYIFPLLQQNCGFGPDSIPQLQDVSDFLKDCTGYTIRPVAGLLSSRDFLAGLAFRVFHSTQYIRHHSAPKYTPEPDICHELLGHVPLFADVEFAQFSQEIGLASLGAPDDIIEKLATLYWFTIEFGICQQDGQVKAYGAGLLSSFGELQYALSDKPQVVDFDPAVCCITKYPITEYQPKYFLAESFASAKNKLKSWASTISRPFQIRYNAYTQRVEILDKVSALQRLARDIRSDMSTLEEALGKVN |
Sequence similarities
Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length474
- Mass (Da)53,945
- Last updated2024-05-29 v1
- Checksum8F3C28B423403DCB