A0AAE7MPX8 · A0AAE7MPX8_ENTGA
- ProteinPhenylalanine--tRNA ligase alpha subunit
- GenepheS
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids347 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- tRNA(Phe) + L-phenylalanine + ATP = L-phenylalanyl-tRNA(Phe) + AMP + diphosphate + H+
Cofactor
Note: Binds 2 magnesium ions per tetramer.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | magnesium ion binding | |
Molecular Function | phenylalanine-tRNA ligase activity | |
Molecular Function | transferase activity | |
Molecular Function | tRNA binding | |
Biological Process | phenylalanyl-tRNA aminoacylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePhenylalanine--tRNA ligase alpha subunit
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Lactobacillales > Enterococcaceae > Enterococcus
Accessions
- Primary accessionA0AAE7MPX8
Proteomes
Subcellular Location
Interaction
Subunit
Tetramer of two alpha and two beta subunits.
Structure
Family & Domains
Features
Showing features for coiled coil, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Coiled coil | 67-94 | |||||
Sequence: RDAITQAIEEAKTSLEAAALEKALAEES | ||||||
Domain | 111-343 | Aminoacyl-transfer RNA synthetases class-II family profile | ||||
Sequence: VLTQIMEEIEDIFVGMGYQVVEGFEVEKDHYNFERMNLPKDHPARDMQDTFYISDEVLIRTHTSPVQARTMEKHDFSKGPLRMISPGKVFRRDTDDATHSHQFHQIEGLVIDKNVTMGDLKGTLEVMMQKMFGADRSIRLRPSYFPFTEPSVEVDVSCFKCGGAGCNVCKHTGWIEILGAGMVHPNVLEMSGIDSKEYSGFAFGLGPDRVAMLRYGVNDIRNFYQNDVRFISQ |
Sequence similarities
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length347
- Mass (Da)39,171
- Last updated2024-05-29 v1
- ChecksumDF9517BA122F3E87