A0AAE6YCG0 · A0AAE6YCG0_STRAT

Function

function

Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.

Features

Showing features for site, active site, binding site.

Type
IDPosition(s)Description
Site107Transition state stabilizer
Active site111Proton acceptor
Binding site274Fe (UniProtKB | ChEBI) of heme b (UniProtKB | ChEBI); axial binding residue

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functioncatalase activity
Molecular Functionheme binding
Molecular Functionmetal ion binding
Biological Processcellular response to hydrogen peroxide
Biological Processhydrogen peroxide catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Catalase-peroxidase
  • EC number
  • Short names
    CP
  • Alternative names
    • Peroxidase/catalase

Gene names

    • Name
      katG
    • ORF names
      HCX60_29400

Organism names

  • Taxonomic identifier
  • Strain
    • DSM 41481
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Kitasatosporales > Streptomycetaceae > Streptomyces

Accessions

  • Primary accession
    A0AAE6YCG0

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for cross-link.

TypeIDPosition(s)Description
Cross-link233↔259Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-110)

Post-translational modification

Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.

Interaction

Subunit

Homodimer or homotetramer.

Family & Domains

Features

Showing features for region, domain.

Type
IDPosition(s)Description
Region1-40Disordered
Domain144-431Plant heme peroxidase family profile

Sequence similarities

Belongs to the peroxidase family. Peroxidase/catalase subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    740
  • Mass (Da)
    80,546
  • Last updated
    2024-05-29 v1
  • Checksum
    179D25A290D57E21
MSENHDAIVTDAKDATGATEGCPVAHGRAAHPTQGGGNRQWWPERLNLKILAKNPDVANPLGADFDYAEAFKNLDLAAVKQDIAEVLTTSQDWWPADFGNYGPLMIRMAWHSAGTYRISDGRGGAGAGQQRFAPLNSWPDNANLDKARRLLWPVKKKYGQSLSWADLLVLTGNVALETMGFETFGFGGGRADVWEAEEDVYWGPETTWLDDRRYSGDRELENPLGAVQMGLIYVNPEGPNGNPDPIAAARDIRETFRRMAMNDEETVALIAGGHTFGKTHGAGPADNVGDDPEAAPLEEQGLGWKSTYGTGKGGDTITSGLEVTWTSTPTRWSNGFFKNLFEYEYELTESPAGAKQWVAKDAEAIIPDAHDPSKKHLPTMLTTDLSLRFDPVYEQISRRFYENPDQFADAFARAWYKLTHRDMGPKSLYLGPEVPEETLLWQDPLPQAEGEPIDAADVTALKAKLLASGLSVSQLVSTAWASASTFRGSDKRGGANGARIRLEPQRGWEANDPDQLRHVLSVLEGVQAEFNTGAKKVSLADLIVLGGAAAVEKAAGDAGFDVEVPFTPGRVDATEEHTDAESFAALEPAWDGFRNYVGKGTRLPAEYLLLDKANLLTLSAPETTVLVGGLRVLGANTGQSSHGVFTDTPGVLTNDFFVNLLDLGTTWKSTSSDQHTFEGRDAATGELKWTGTRADLVFGSNSELRALAEVYASDDAKEKFVKDFVDAWVKVSNLDRFDLI

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP050692
EMBL· GenBank· DDBJ
QIT47128.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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