A0AAE5CDV8 · A0AAE5CDV8_RHOHA
- ProteinSmall ribosomal subunit biogenesis GTPase RsgA
- GenersgA
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids394 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
Cofactor
Note: Binds 1 zinc ion per subunit.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 186-189 | GTP (UniProtKB | ChEBI) | ||||
Sequence: TKAD | ||||||
Binding site | 237-245 | GTP (UniProtKB | ChEBI) | ||||
Sequence: GPSGAGKSS | ||||||
Binding site | 318 | Zn2+ (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 323 | Zn2+ (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 325 | Zn2+ (UniProtKB | ChEBI) | ||||
Sequence: H | ||||||
Binding site | 331 | Zn2+ (UniProtKB | ChEBI) | ||||
Sequence: C |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | GTP binding | |
Molecular Function | GTPase activity | |
Molecular Function | metal ion binding | |
Molecular Function | rRNA binding | |
Biological Process | ribosomal small subunit biogenesis |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameSmall ribosomal subunit biogenesis GTPase RsgA
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Mycobacteriales > Nocardiaceae > Prescottella
Accessions
- Primary accessionA0AAE5CDV8
Proteomes
Subcellular Location
Interaction
Subunit
Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-47 | Disordered | ||||
Sequence: MRNSAPRVKRVLGRGPIPKGLTMSSSPSSSSPSSSSPSPNSPAHGLA | ||||||
Compositional bias | 21-42 | Polar residues | ||||
Sequence: LTMSSSPSSSSPSSSSPSPNSP | ||||||
Domain | 141-295 | CP-type G | ||||
Sequence: HRQVLAANVDTACVVVSLAAPIKPGRIERLLALAWDAGTTPLIVLTKADAAECDPGTAAAEVSALAIGVDVVTVSARTGEGIDELARRLPGTTVLLGPSGAGKSSLTNALLGEDRMDTNEVRATDGKGRHTTVHRELFPVPGGGVLIDTPGLRGI | ||||||
Domain | 147-293 | EngC GTPase | ||||
Sequence: ANVDTACVVVSLAAPIKPGRIERLLALAWDAGTTPLIVLTKADAAECDPGTAAAEVSALAIGVDVVTVSARTGEGIDELARRLPGTTVLLGPSGAGKSSLTNALLGEDRMDTNEVRATDGKGRHTTVHRELFPVPGGGVLIDTPGLR |
Sequence similarities
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
Family and domain databases
Sequence
- Sequence statusComplete
- Length394
- Mass (Da)41,699
- Last updated2024-05-29 v1
- Checksum5D9138251C5F4E84
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 21-42 | Polar residues | ||||
Sequence: LTMSSSPSSSSPSSSSPSPNSP |