A0AAE4TTG8 · A0AAE4TTG8_STRCB
- ProteintRNA pseudouridine synthase A
- GenetruA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids249 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
Catalytic activity
- uridine(38/39/40) in tRNA = pseudouridine(38/39/40) in tRNA
RHEA-COMP:10085 = RHEA-COMP:10087
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 53 | Nucleophile | ||||
Sequence: D | ||||||
Binding site | 111 | substrate | ||||
Sequence: Y |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | catalytic activity, acting on RNA | |
Molecular Function | pseudouridine synthase activity | |
Molecular Function | RNA binding | |
Biological Process | tRNA pseudouridine synthesis |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nametRNA pseudouridine synthase A
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Lactobacillales > Streptococcaceae > Streptococcus
Accessions
- Primary accessionA0AAE4TTG8
Proteomes
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 6-104 | Pseudouridine synthase I TruA alpha/beta | ||||
Sequence: ATISYDGTLFSGFQRQSHVRTVQEEIEKTLQKLASGQQILIHGAGRTDTGVHAYGQVIHFDLPQKRDLEKLRFALDTQTPDDIDVIKLEIVADDFHCRY | ||||||
Domain | 144-248 | Pseudouridine synthase I TruA alpha/beta | ||||
Sequence: AIKDLVGTHDFTGFTAAGTSVENKVRTITEATLIQDDKTGFLVFTFSGNGFLYKQVRNMVGTLLKIGNGRMPVEQIKVILASKNRQLAGPTPAGNGLYLKEIRYE |
Sequence similarities
Belongs to the tRNA pseudouridine synthase TruA family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length249
- Mass (Da)28,237
- Last updated2024-05-29 v1
- Checksum6F0D325B21F949BC