A0AAE4Q5N7 · A0AAE4Q5N7_STRCB

  • Protein
    Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
  • Gene
    glmS
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Features

Showing features for active site.

160450100150200250300350400450500550600
TypeIDPosition(s)Description
Active site2Nucleophile; for GATase activity
Active site599For Fru-6P isomerization activity

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functioncarbohydrate derivative binding
Molecular Functionglutamine-fructose-6-phosphate transaminase (isomerizing) activity
Biological Processcarbohydrate metabolic process
Biological Processfructose 6-phosphate metabolic process
Biological Processglutamine metabolic process
Biological Processprotein N-linked glycosylation
Biological ProcessUDP-N-acetylglucosamine metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
  • EC number
  • Alternative names
    • D-fructose-6-phosphate amidotransferase
    • GFAT
    • Glucosamine-6-phosphate synthase
    • Hexosephosphate aminotransferase
    • L-glutamine--D-fructose-6-phosphate amidotransferase

Gene names

    • Name
      glmS
    • ORF names
      KB584_00720

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • 284
  • Taxonomic lineage
    Bacteria > Bacillota > Bacilli > Lactobacillales > Streptococcaceae > Streptococcus

Accessions

  • Primary accession
    A0AAE4Q5N7

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for initiator methionine.

TypeIDPosition(s)Description
Initiator methionine1Removed

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain2-218Glutamine amidotransferase type-2
Domain284-423SIS
Domain456-594SIS

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    604
  • Mass (Da)
    65,514
  • Last updated
    2024-05-29 v1
  • Checksum
    916D22C459B32691
MCGIVGVVGNRNATDILMQGLEKLEYRGYDSAGIFVANDNQSNLIKSVGRITDLRAKIGIDVAGSTGIGHTRWATHGQSTEGNAHPHTSQTGRFVLVHNGVIENYLHIKTEFLAGHDFKGQTDTEIAVHLIGKFVEEDKLSVLEAFKKALNIIEGSYAFALMDSQATDTIYVAKNKSPLLIGLGEGYNMICSDAMAMIRETSEFMEIHDKEVVVLTKDSIMITDYDGQVVKRNAYTAELDLSDIGKGTYPFYMLKEIDEQPTVMRRLISTYADESGKMLLDSAIISSIQEADRLYILAAGTSYHAGFATKNMLEQLTDTPVELGVASEWGYHMPLLSKKPMFILLSQSGETADSRQVLVKANAMGIPSLTVTNVPGSTLSREATYTMLIHAGPEIAVASTKAYTAQIAALAFLAKAVGEANGKQEAIDFNLAHELSLVAQSIEATLTEKNLVAEKVQALLSTTRSAFYIGRGNDYYVAMEAALKLKEISYIQCEGFAAGELKHGTISLIEEGTPVIGLISSSQLVASHTRGNIQEVAARGAHVLTVVEEGLEREGDDIIVNKVHPFLAPIAMVIPTQLIAYYASLQRGLDVDKPRNLAKAVTVE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAGQEX010000001
EMBL· GenBank· DDBJ
MDV5976018.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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