A0AAE3TEK4 · A0AAE3TEK4_9BACT

Function

function

Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • ATP-dependent cleavage of peptide bonds with broad specificity.
    EC:3.4.25.2 (UniProtKB | ENZYME | Rhea)

Activity regulation

Allosterically activated by HslU binding.

Features

Showing features for active site, binding site.

117520406080100120140160
Type
IDPosition(s)Description
Active site5
Binding site160Na+ (UniProtKB | ChEBI)
Binding site163Na+ (UniProtKB | ChEBI)
Binding site166Na+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular ComponentHslUV protease complex
Cellular Componentproteasome core complex
Molecular Functionmetal ion binding
Molecular Functionthreonine-type endopeptidase activity
Biological Processproteolysis involved in protein catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ATP-dependent protease subunit HslV
  • EC number

Gene names

    • Name
      hslV
    • ORF names
      OD816_001329

Organism names

Accessions

  • Primary accession
    A0AAE3TEK4

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.

Family & Domains

Sequence similarities

Belongs to the peptidase T1B family. HslV subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    175
  • Mass (Da)
    18,856
  • Last updated
    2024-05-29 v1
  • MD5 Checksum
    A8BF0DEFD608D7A35D8A5DC35D21930B
MFKGTTVIAVKKDGKIAMAGDGQVTFGNTILKHRAKKIRKLYKGKVLAGFAGATADAFTLFERLEKKLEAYSGQLLRAAVELAKDWRTDKVLRRLEAFLIACDSDHLLLISGAGDVVEPDENIIAIGSGGPMALAAAKALLRHTSLSAREIAEISIKIAGEICIYTNSEIVVEEL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAPHEG010000006
EMBL· GenBank· DDBJ
MDF2954084.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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