A0AAE3TEF8 · A0AAE3TEF8_9BACT
- ProteinPhosphoheptose isomerase
- GenegmhA
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids195 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
Miscellaneous
The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.
Catalytic activity
- 2 D-sedoheptulose 7-phosphate = D-glycero-alpha-D-manno-heptose 7-phosphate + D-glycero-beta-D-manno-heptose 7-phosphate
Cofactor
Note: Binds 1 zinc ion per subunit.
Pathway
Carbohydrate biosynthesis; D-glycero-D-manno-heptose 7-phosphate biosynthesis; D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate from sedoheptulose 7-phosphate: step 1/1.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 54-56 | substrate | |||
Binding site | 63 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 67 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 67 | substrate | |||
Binding site | 96-97 | substrate | |||
Binding site | 122-124 | substrate | |||
Binding site | 127 | substrate | |||
Binding site | 174 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 174 | substrate | |||
Binding site | 182 | Zn2+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | carbohydrate derivative binding | |
Molecular Function | D-sedoheptulose 7-phosphate isomerase activity | |
Molecular Function | zinc ion binding | |
Biological Process | carbohydrate derivative metabolic process | |
Biological Process | carbohydrate metabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePhosphoheptose isomerase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Thermodesulfobacteriota > Thermodesulfobacteria > Thermodesulfobacteriales > Thermodesulfobacteriaceae > Thermodesulfobacterium
Accessions
- Primary accessionA0AAE3TEF8
Proteomes
Subcellular Location
Structure
Sequence
- Sequence statusComplete
- Length195
- Mass (Da)21,402
- Last updated2024-05-29 v1
- MD5 ChecksumC289DAEB77B497AE92BC11B9A499F719
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JAPHEG010000002 EMBL· GenBank· DDBJ | MDF2953426.1 EMBL· GenBank· DDBJ | Genomic DNA |