A0AAE3TEF8 · A0AAE3TEF8_9BACT

Function

function

Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.

Miscellaneous

The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Pathway

Carbohydrate biosynthesis; D-glycero-D-manno-heptose 7-phosphate biosynthesis; D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate from sedoheptulose 7-phosphate: step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site54-56substrate
Binding site63Zn2+ (UniProtKB | ChEBI)
Binding site67Zn2+ (UniProtKB | ChEBI)
Binding site67substrate
Binding site96-97substrate
Binding site122-124substrate
Binding site127substrate
Binding site174Zn2+ (UniProtKB | ChEBI)
Binding site174substrate
Binding site182Zn2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functioncarbohydrate derivative binding
Molecular FunctionD-sedoheptulose 7-phosphate isomerase activity
Molecular Functionzinc ion binding
Biological Processcarbohydrate derivative metabolic process
Biological Processcarbohydrate metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphoheptose isomerase
  • EC number
  • Alternative names
    • Sedoheptulose 7-phosphate isomerase

Gene names

    • Name
      gmhA
    • ORF names
      OD816_000671

Organism names

Accessions

  • Primary accession
    A0AAE3TEF8

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain38-195SIS

Sequence similarities

Belongs to the SIS family. GmhA subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    195
  • Mass (Da)
    21,402
  • Last updated
    2024-05-29 v1
  • MD5 Checksum
    C289DAEB77B497AE92BC11B9A499F719
MKKSQLRKRIFEISESSREVQKAFIEIESEKIMEVVYLAKKVISKNGKILIFGNGGSAADAQHLAAELVNRFKKERSPMPAIALTTDTSILTAVANDYDFSEVFSKQILALGKKGDIALGISTSGKSANVISALKVAKKLGMHTVGLSGGDGGLMKELCDYLILVPSYETPRIQEGHLLFLHIFSELLEELIFQE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAPHEG010000002
EMBL· GenBank· DDBJ
MDF2953426.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our Privacy Notice.
Help