A0AAE3RHF2 · A0AAE3RHF2_9ENTR
- ProteinPyruvate dehydrogenase E1 component
- GeneaceE
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids887 (go to sequence)
- Protein existencePredicted
- Annotation score2/5
Function
function
Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
Catalytic activity
- N6-[(R)-lipoyl]-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase] + pyruvate + H+ = N6-[(R)-S8-acetyldihydrolipoyl]-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase] + CO2
Cofactor
Protein has several cofactor binding sites:
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 231 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 261 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 263 | Mg2+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | metal ion binding | |
Molecular Function | oxidoreductase activity |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePyruvate dehydrogenase E1 component
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Klebsiella/Raoultella group > Klebsiella
Accessions
- Primary accessionA0AAE3RHF2
Proteomes
Sequence
- Sequence statusComplete
- Length887
- Mass (Da)99,434
- Last updated2024-05-29 v1
- Checksum72F31E1AF7E90B83
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JAKUZO010000005 EMBL· GenBank· DDBJ | MDK1964913.1 EMBL· GenBank· DDBJ | Genomic DNA |