A0AAE3RHF2 · A0AAE3RHF2_9ENTR

  • Protein
    Pyruvate dehydrogenase E1 component
  • Gene
    aceE
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Predicted
  • Annotation score
    2/5

Function

function

Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

thiamine diphosphate (UniProtKB | Rhea| CHEBI:58937 )

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site231Mg2+ (UniProtKB | ChEBI)
Binding site261Mg2+ (UniProtKB | ChEBI)
Binding site263Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionmetal ion binding
Molecular Functionoxidoreductase activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Pyruvate dehydrogenase E1 component
  • EC number

Gene names

    • Name
      aceE
    • ORF names
      MKS10_11430

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • K5-229
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Klebsiella/Raoultella group > Klebsiella

Accessions

  • Primary accession
    A0AAE3RHF2

Proteomes

Structure

3D structure databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain133-294Transketolase N-terminal
Domain488-700Pyruvate dehydrogenase E1 component middle
Domain713-845Transketolase-like C-terminal

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    887
  • Mass (Da)
    99,434
  • Last updated
    2024-05-29 v1
  • Checksum
    72F31E1AF7E90B83
MSERLHNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLSEARKGGVKVAAGASAGNYVNTIAVEDEPEYPGNLDLERRIRSAIRWNAIMTVLRASKKDLELGGHMASYQSSATFYEVCFNHFFRARTEKDGGDLVYFQGHISPGVYARAFLEGRLTEEQMDNFRQEVHGKGLSSYPHPKLMPEFWQFPTVSMGLGPLGAIYQAKFLKYLEHRGLKDTSEQTVYAFLGDGEMDEPESKGAITIATREKLDNLVFVINCNLQRLDGPVTGNGKIINELEGIFGGAGWNVIKVIWGGRWDELLRKDTSGKLIQLMNETVDGDYQTFKSKDGAYVREHFFGKYPETAALVADWTDEQIWALNRGGHDPKKVYAALKKAQETKGQPTVILAHTIKGYGMGDTAEGKNIAHQVKKMNMDGVRYVRDRFNVPVADADLEKLPYVTFPEGSEEHTYLHAQRQKLNGYLPTRQPKFTEKLELPTLADFSALLEEQNKEISTTIAFVRALNVMLKNKSIKDRLVPIIADEARTFGMEGLFRQIGIYSPNGQQYTPQDREQVAYYKEDEKGQILQEGINELGAGASWLAAATSYSTNNLPMIPFYIYYSMFGFQRIGDLCWAAGDQQARGFLIGGTSGRTTLNGEGLQHEDGHSHIQSLTIPNCISYDPAYAYEVAVIMHDGLVRMYGEAQENVYYYITTLNENYHMPAMPEGAEEGIRKGIYKLETIEGSKGKVQLLGSGSILRHVREAAQILAKDYGVGSDVYSVTSFTELARDGQDCERWNMLHPLETPRVPYIAQVMNDAPAVASTDYMKLFAEQVRTYVPADDYRVLGTDGFGRSDSRENLRHHFEVDASYVVVAALGELAKRGEIDKKVVADAIAKFDIDAEKVNPRLA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAKUZO010000005
EMBL· GenBank· DDBJ
MDK1964913.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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