A0AAE3RC43 · A0AAE3RC43_9ENTR

  • Protein
    Glucose-6-phosphate 1-dehydrogenase
  • Gene
    zwf
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site50NADP+ (UniProtKB | ChEBI)
Binding site92-93NADP+ (UniProtKB | ChEBI)
Binding site147NADP+ (UniProtKB | ChEBI)
Binding site177substrate
Binding site181substrate
Binding site215substrate
Binding site234substrate
Active site239Proton acceptor
Binding site339substrate
Binding site344substrate

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionglucose-6-phosphate dehydrogenase activity
Molecular FunctionNADP binding
Biological Processglucose metabolic process
Biological Processpentose-phosphate shunt, oxidative branch

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glucose-6-phosphate 1-dehydrogenase
  • EC number
  • Short names
    G6PD

Gene names

    • Name
      zwf
    • ORF names
      MKS10_00525

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • K5-229
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Klebsiella/Raoultella group > Klebsiella

Accessions

  • Primary accession
    A0AAE3RC43

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain13-186Glucose-6-phosphate dehydrogenase NAD-binding
Domain188-488Glucose-6-phosphate dehydrogenase C-terminal

Sequence similarities

Belongs to the glucose-6-phosphate dehydrogenase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    491
  • Mass (Da)
    55,872
  • Last updated
    2024-05-29 v1
  • MD5 Checksum
    F10ED7407D356B4BC84A876A1DEA577D
MAVTQTAQACDLVIFGAKGDLARRKLLPSLYQLEKAGQIHADTRIIGVGRADWDKAAYTKVVREALETFMKEKIDEGLWDTLSGRLEFCNLDVNDTSGFTRLGEMLDQKNRVTINYFAMPPSTFGAICKGLGEAKLNAKPARVVMEKPLGTSLETSREINDQVGEFFEECQVYRIDHYLGKETVLNLLALRFANSLFVNNWDCRTIDHVEITVAEEVGIEGRWGYFDQAGQMRDMIQNHLLQILCMIAMSPPSDLSADSIRDEKVKVLKSLRRIDRSNVREKTVRGQYTAGFAQGKKVPGYLEEEGANKTSNTETFVAIRVDIDNWRWAGVPFYLRTGKRLPTKCSEVVVYFKTPELNLFKETWQELPQNKLTIRLQPDEGVDIQVLNKVPGLDHKHNLQITKLDLSYSETFNQTHLADAYERLLLETMRGIQALFVRRDEVEEAWKWVDSITEAWAADRDAPKPYQAGTWGPVASVAMITRDGRSWNEFE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAKUZO010000001
EMBL· GenBank· DDBJ
MDK1962833.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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