A0AAE3MNC4 · A0AAE3MNC4_9BURK

  • Protein
    Amidophosphoribosyltransferase
  • Gene
    purF
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 1 Mg2+ ion per subunit.

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; N1-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/2.

Features

Showing features for active site, binding site.

TypeIDPosition(s)Description
Active site2Nucleophile
Binding site305Mg2+ (UniProtKB | ChEBI)
Binding site367Mg2+ (UniProtKB | ChEBI)
Binding site368Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionamidophosphoribosyltransferase activity
Molecular Functionmagnesium ion binding
Biological Process'de novo' IMP biosynthetic process
Biological Processglutamine metabolic process
Biological Processpurine nucleobase biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Amidophosphoribosyltransferase
  • EC number
  • Short names
    ATase
  • Alternative names
    • Glutamine phosphoribosylpyrophosphate amidotransferase
      (GPATase
      )

Gene names

    • Name
      purF
    • ORF names
      OSH04_00920

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • A-TC2
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Alcaligenaceae > Alcaligenes

Accessions

  • Primary accession
    A0AAE3MNC4

Proteomes

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain2-236Glutamine amidotransferase type-2

Sequence similarities

In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    494
  • Mass (Da)
    54,644
  • Last updated
    2024-05-29 v1
  • Checksum
    76F1CBA1A9C6EBA7
MCGVVGVVARSPVNQLIYDSLLLLQHRGQDAAGLATWHDQFFSMHKAFGLVRDVFRTRNMRSLPGNSGIGHVRYPTAGSSQSVEEAQPFYVNAPFGLSFVHNGNLTNWRELREELFTIDRRHINTNSDSEVLLNVYAHELQRAATGPELTQDEVFEAVAAVHRRARGAYAVVSQIANFGLVAFRDPNGIRPLCLGRNVTPKGEEWMIASESVALTGCGFELVRDVEPGEAIIVDLDGNLSSRQCAENPRLNPCVFEYVYFARPDSTVDGVSVYDARLLMGEYLAENVAKNLRLADIDVVMPIPDSARPSAMQLAAHLNLNYREGFIKNRYVGRTFIMPGQEVRKKSVRQKLSAIPMEFRGKNVLLVDDSIVRGTTSRQIVDMARAAGANKVFFASAAPPVRFPNVYGIDMPTVSELIATGRDVDQVAKEIGVDGLVYQDLHDLEQSLRDLNPRFAGFESSCFSGEYVTGDVDEAYLNLLAEGRKNGREVPDVTD

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAPKMZ010000001
EMBL· GenBank· DDBJ
MCX5470267.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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