A0AAE2BUS2 · A0AAE2BUS2_9LAMI
- Proteinaspartate carbamoyltransferase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids425 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the condensation of carbamoyl phosphate and aspartate to form carbamoyl aspartate and inorganic phosphate, the committed step in the de novo pyrimidine nucleotide biosynthesis pathway.
Catalytic activity
- carbamoyl phosphate + L-aspartate = N-carbamoyl-L-aspartate + phosphate + H+
Pathway
Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 2/3.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Molecular Function | amino acid binding | |
Molecular Function | aspartate carbamoyltransferase activity | |
Biological Process | 'de novo' pyrimidine nucleobase biosynthetic process | |
Biological Process | amino acid metabolic process | |
Biological Process | pyrimidine nucleotide biosynthetic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameaspartate carbamoyltransferase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > asterids > lamiids > Lamiales > Pedaliaceae > Sesamum
Accessions
- Primary accessionA0AAE2BUS2
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 399-416 | Helical | |||
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-21 | ||||
Chain | PRO_5042277317 | 22-425 | aspartate carbamoyltransferase | ||
Interaction
Subunit
Homotrimer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 109-250 | Aspartate/ornithine carbamoyltransferase carbamoyl-P binding | |||
Domain | 257-408 | Aspartate/ornithine carbamoyltransferase Asp/Orn-binding | |||
Sequence similarities
Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length425
- Mass (Da)47,493
- Last updated2024-05-29 v1
- ChecksumFD1D8B0059534DDD
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JACGWL010000007 EMBL· GenBank· DDBJ | KAK4398554.1 EMBL· GenBank· DDBJ | Genomic DNA |