A0AAD9WGU6 · A0AAD9WGU6_EUCGR

Function

function

Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Sulfur metabolism; glutathione metabolism.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site140L-glutamate (UniProtKB | ChEBI)
Active site410Nucleophile
Binding site428-430L-glutamate (UniProtKB | ChEBI)
Binding site452L-glutamate (UniProtKB | ChEBI)
Binding site480-481L-glutamate (UniProtKB | ChEBI)
Binding site502L-glutamate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmembrane
Molecular Functionacyltransferase activity
Molecular Functionglutathione hydrolase activity
Biological Processglutathione catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glutathione hydrolase
  • EC number
  • Alternative names
    • Gamma-glutamyltransferase
    • Gamma-glutamyltranspeptidase

Gene names

    • ORF names
      EUGRSUZ_L03417

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Myrtales > Myrtaceae > Myrtoideae > Eucalypteae > Eucalyptus

Accessions

  • Primary accession
    A0AAD9WGU6

Proteomes

Subcellular Location

Membrane
; Single-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane23-43Helical

Keywords

  • Cellular component

PTM/Processing

Keywords

Family & Domains

Sequence similarities

Belongs to the gamma-glutamyltransferase family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    625
  • Mass (Da)
    67,131
  • Last updated
    2024-05-29 v1
  • Checksum
    451FA9F09711EEBF
MDAPLLGSHDLIRHEEKPGRRNWTKALCFFLAFVSVTVLGLVVSGDIHARAVGVGSKYSGSILNDAIVVESEKGVVAADDGRCSEIGASMLRKGGHAVDAAVATALCVGVVNSMASGIGGGAFMIVQSSSTLKTEAYDSRETAPLAASQDMYENNPSAKYYGALSMGVPGEIAGLHQAWLKHGRLPWRTFFQPSIKLAKEGFVVAPYLAHHIANAAERILDDPGLRQVFAPGGKLLRAGDTCYNVELGQSLEAIAEQGPQAFYNGSVGEKLVKDVREAGGILTMEDLRNYKVEVTDAMSAEVMGYTIFGMQPPSSGTLGLSLIMNILNSYGNSNAVEGSLGMHRLIEAMKHMFAIRMNLGDPNFVSIDEYVSQMLSPSFAKQLRQKILDDTTFPSEYYLYKWSQLRDHGTSHFGIVDADRNAVSMTTTVNYPFGGGVLSPTTGIVLNNEMGDFSTPTEISPDHLPPAPANFIEPNKRPLSSMTPLIISKDNQLAGVVGGSGGMNIIPAVTQVFLNHFVLGMEPLDAVKDPRVYHRLIPNVVMYENCTCINGIHIELSDKRKLFLKGIGHQLEAIAGGAIVQLVVQNLQDTLDLGRKSRKGLNSGIVRGTLTAVSDPRKDGKPAAV

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A0AAD9WI81A0AAD9WI81_EUCGREUGRSUZ_L03417622

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MU851180
EMBL· GenBank· DDBJ
KAK2631094.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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