A0AAD9WGU6 · A0AAD9WGU6_EUCGR
- ProteinGlutathione hydrolase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids625 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
Catalytic activity
- an S-substituted glutathione + H2O = an S-substituted L-cysteinylglycine + L-glutamate
Pathway
Sulfur metabolism; glutathione metabolism.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 140 | L-glutamate (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Active site | 410 | Nucleophile | ||||
Sequence: T | ||||||
Binding site | 428-430 | L-glutamate (UniProtKB | ChEBI) | ||||
Sequence: TVN | ||||||
Binding site | 452 | L-glutamate (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 480-481 | L-glutamate (UniProtKB | ChEBI) | ||||
Sequence: SS | ||||||
Binding site | 502 | L-glutamate (UniProtKB | ChEBI) | ||||
Sequence: G |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Molecular Function | acyltransferase activity | |
Molecular Function | glutathione hydrolase activity | |
Biological Process | glutathione catabolic process |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGlutathione hydrolase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Myrtales > Myrtaceae > Myrtoideae > Eucalypteae > Eucalyptus
Accessions
- Primary accessionA0AAD9WGU6
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Single-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 23-43 | Helical | ||||
Sequence: WTKALCFFLAFVSVTVLGLVV |
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Structure
Sequence
- Sequence statusComplete
- Length625
- Mass (Da)67,131
- Last updated2024-05-29 v1
- Checksum451FA9F09711EEBF
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0AAD9WI81 | A0AAD9WI81_EUCGR | EUGRSUZ_L03417 | 622 |
Keywords
- Technical term