A0AAD9T8N5 · A0AAD9T8N5_EUCGR
- Proteinlactoylglutathione lyase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids327 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
Catalytic activity
- (R)-S-lactoylglutathione = methylglyoxal + glutathione
Cofactor
Note: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.
Pathway
Secondary metabolite metabolism; methylglyoxal degradation; (R)-lactate from methylglyoxal: step 1/2.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 120 | Zn2+ (UniProtKB | ChEBI); ligand shared between dimeric partners | |||
Binding site | 137 | Zn2+ (UniProtKB | ChEBI); ligand shared between dimeric partners | |||
Active site | 185 | Proton donor/acceptor | |||
Binding site | 185 | Zn2+ (UniProtKB | ChEBI); ligand shared between dimeric partners | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | lactoylglutathione lyase activity | |
Molecular Function | metal ion binding |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namelactoylglutathione lyase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Myrtales > Myrtaceae > Myrtoideae > Eucalypteae > Eucalyptus
Accessions
- Primary accessionA0AAD9T8N5
Proteomes
Structure
Sequence
- Sequence statusComplete
- Length327
- Mass (Da)36,408
- Last updated2024-05-29 v1
- MD5 ChecksumC1432311ADE494ECC445C6858841B59F
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
MU851219 EMBL· GenBank· DDBJ | KAK2631087.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MU851219 EMBL· GenBank· DDBJ | KAK2631088.1 EMBL· GenBank· DDBJ | Genomic DNA |