A0AAD9RNG0 · A0AAD9RNG0_9HYME

Function

function

The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization.
Transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non-muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell adhesion-mediated signaling and implicated in cell polarity.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoskeleton
Cellular Componentdystroglycan complex
Cellular Componentextracellular region
Cellular Componentnucleoplasm
Cellular Componentpostsynaptic membrane
Cellular Componentsarcolemma
Molecular Functioncalcium ion binding
Molecular Functionlaminin binding
Biological Processaxon guidance
Biological Processmorphogenesis of an epithelium
Biological Processmuscle attachment
Biological Processnerve development

Names & Taxonomy

Protein names

  • Recommended name
    Dystroglycan 1
  • Alternative names
    • Dystroglycan
    • Dystrophin-associated glycoprotein 1

Gene names

    • ORF names
      KPH14_008970

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • GBR_01_08_01A
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Hymenoptera > Apocrita > Aculeata > Vespoidea > Vespidae > Eumeninae > Odynerus

Accessions

  • Primary accession
    A0AAD9RNG0

Proteomes

Subcellular Location

Cell membrane, sarcolemma
Cell membrane
; Single-pass type I membrane protein
Cytoplasm, cytoskeleton
Membrane
; Single-pass type I membrane protein
Nucleus, nucleoplasm
Postsynaptic cell membrane
Secreted, extracellular space
Synaptic cell membrane

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane1161-1187Helical

Keywords

PTM/Processing

Features

Showing features for signal, chain.

TypeIDPosition(s)Description
Signal1-18
ChainPRO_504222164019-1300Dystroglycan 1

Keywords

Family & Domains

Features

Showing features for region, compositional bias, domain.

TypeIDPosition(s)Description
Region32-52Disordered
Compositional bias36-52Basic and acidic residues
Region302-385Disordered
Compositional bias319-343Acidic residues
Compositional bias362-385Basic and acidic residues
Region410-507Disordered
Region598-655Disordered
Compositional bias614-655Polar residues
Domain777-890Peptidase S72
Domain1018-1130Peptidase S72
Compositional bias1194-1208Basic and acidic residues
Region1194-1300Disordered
Compositional bias1215-1232Basic and acidic residues

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,300
  • Mass (Da)
    144,228
  • Last updated
    2024-05-29 v1
  • Checksum
    3BE69138095AEF60
MKKPHILTYLLILPLVLGFTLQEDDLVFDDVGEENSSGPSIERHLEDRGRSVHDRRSTKDTWRHHRVERLWGVPDVVVPVGHVFKMRISKQAFGGSVDRYEIHEANGQNLSGWLYWDDAASTLLGVPSKKDIGNHHVTVKAIGKHGDSAKDAFVVQVVSEKREEVKHKDGKTHCNEGEDQTLLTILLHAKFENLTPPVKVNAIENLAGFLGLHTSAFSMHPQNAKDNPNSDSMIIFTGAGNVKYRTEKHLTTIQWQVGCDGHIWRHQTDLVKQLRDQAKDGTLAEVLQLPVLSWRVKTESTSLSRSRREVGSGNFDADEYGYDYDEEYDEEDEEDEEGADENEAITEQPLPPSFVPHSKAKGNVEWSEHPHRHHHGEETLDWNNEEVDEREIIPSIDPRIAESVNSNSTFAAPSTTTATSFTPSSSSTTTTITTTMPTTTSSATTQATTMPTSITTTTSPTTTTTTTTTTSTTTTSTIADTTPATTTTTTTTTTPSTVVPSTESTRVDIMEESGENTQRADVESVTLLPTISPEITTTLPSITTTLQFSTTAASSSATGKSETEATTVIANVTSEEQTDATMIPSTRQPTTIPIASSTTVTSTNAPTTIPPTQPPTVSTVRTTEMPTTTSTTTVATTTTSTTTTTTQAPTSATIPPLQATTDSVELAANLPPKKDRRLKKIPVTAGKILSYVIPADTFSDLEDGDTRNLKLSLYTQGVPIKNTHWLQFNPHTQEVYGLPLENDISIWDYELVATDSGGLNVTDRLDVHVQQHKLSRTVNHEFSIYLKIDKRNLFPTNVDWELQVIEKLAKLYDDPDPHYITVRSVQIDHDQAIFTWTNDSLPRSSECPKEHINQLLNVLVDKDGDPSPSLRRVLAPEMRVKRVVFQGIGQCEDMSQPEVPKVHTEEPKVNFPPVPRNQVDHINATVGQLLVFKVPEDTFFDAEDGSSRNMKMSLLTIDRTPIPPHEWLQFDSKNQEFYGVPLHNDVGRKEYQLVATDREGASATDGLVVVVHPAPPMKHTVEFSMTLDIPYESFAHSAMQKRNFIEKLRDLYHDRDTSAISLHSISNGSTVITWHNRTLPTSYCAHEEVSRLRAVLVKSDNDRRSVTDEVLEVMGMKFPVKQITVIPMGICLGELTGVHSPDNHVPPVDDSTSVGAFHDDYLITFVLPAIIIAAMLILAGIIACVLYKRRRSGKMSVSEQDDERQSFRSKGIPVIFQDELDEKPDPGNKSPVILKEEKPPLPPPEYQKSEDGADVPMLPKENSEEPYQPPPPFATNRETNRQNRPKPTPTYRKPPPYVPP

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A0AAD9RND5A0AAD9RND5_9HYMEKPH14_0089701139

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias36-52Basic and acidic residues
Compositional bias319-343Acidic residues
Compositional bias362-385Basic and acidic residues
Compositional bias614-655Polar residues
Compositional bias1194-1208Basic and acidic residues
Compositional bias1215-1232Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAIFRP010000030
EMBL· GenBank· DDBJ
KAK2582896.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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