A0AAD9RLE6 · A0AAD9RLE6_9HYME

  • Protein
    Peptidase metallopeptidase domain-containing protein
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Cofactor

Protein has several cofactor binding sites:
Ca2+ (UniProtKB | Rhea| CHEBI:29108 )

Note: Can bind about 5 Ca2+ ions per subunit.
Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 2 Zn2+ ions per subunit.

Features

Showing features for binding site, active site.

162750100150200250300350400450500550600
TypeIDPosition(s)Description
Binding site88Zn2+ 2 (UniProtKB | ChEBI); catalytic; in inhibited form
Binding site163Ca2+ 2 (UniProtKB | ChEBI)
Binding site173Zn2+ 1 (UniProtKB | ChEBI)
Binding site175Zn2+ 1 (UniProtKB | ChEBI)
Binding site180Ca2+ 3 (UniProtKB | ChEBI)
Binding site181Ca2+ 3 (UniProtKB | ChEBI)
Binding site188Zn2+ 1 (UniProtKB | ChEBI)
Binding site197Ca2+ 2 (UniProtKB | ChEBI)
Binding site199Ca2+ 2 (UniProtKB | ChEBI)
Binding site201Zn2+ 1 (UniProtKB | ChEBI)
Binding site203Ca2+ 3 (UniProtKB | ChEBI)
Binding site206Ca2+ 1 (UniProtKB | ChEBI)
Binding site206Ca2+ 3 (UniProtKB | ChEBI)
Binding site227Zn2+ 2 (UniProtKB | ChEBI); catalytic
Active site228
Binding site231Zn2+ 2 (UniProtKB | ChEBI); catalytic
Binding site237Zn2+ 2 (UniProtKB | ChEBI); catalytic
Binding site245Zn2+ 2 (UniProtKB | ChEBI); catalytic
Binding site393Ca2+ 4 (UniProtKB | ChEBI)
Binding site395Ca2+ 5 (UniProtKB | ChEBI)
Binding site440Ca2+ 4 (UniProtKB | ChEBI)
Binding site489Ca2+ 5 (UniProtKB | ChEBI)
Binding site536Ca2+ 4 (UniProtKB | ChEBI)
Binding site538Ca2+ 5 (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentextracellular matrix
Cellular Componentmembrane
Molecular Functionmetalloendopeptidase activity
Molecular Functionzinc ion binding
Biological Processproteolysis

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Peptidase metallopeptidase domain-containing protein

Gene names

    • ORF names
      KPH14_002237

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • GBR_01_08_01A
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Hymenoptera > Apocrita > Aculeata > Vespoidea > Vespidae > Eumeninae > Odynerus

Accessions

  • Primary accession
    A0AAD9RLE6

Proteomes

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane607-626Helical

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain, modified residue.

TypeIDPosition(s)Description
Signal1-17
ChainPRO_504191606618-627Peptidase metallopeptidase domain-containing protein
Modified residue470Phosphotyrosine; by PKDCC

Family & Domains

Features

Showing features for domain, region, compositional bias, repeat.

TypeIDPosition(s)Description
Domain109-272Peptidase metallopeptidase
Region276-362Disordered
Compositional bias294-310Polar residues
Compositional bias315-345Basic and acidic residues
Repeat385-433Hemopexin
Repeat436-481Hemopexin
Repeat483-531Hemopexin
Repeat532-579Hemopexin

Sequence similarities

Belongs to the peptidase M10A family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    627
  • Mass (Da)
    72,171
  • Last updated
    2024-05-29 v1
  • Checksum
    08A15D06B8320BA5
MIFHVMLVLYFSVLVAGAPRSSMIYADDKVQNYLMKFGYLPQSNLETGNLMTEDQLRDAIKNLQRFSGIPETGEIDDTTRKLMKARRCGLPDKPNPRYSRTRRKRFTIHGQQWPYRNLTWSLRTKQPSGLETGGVRLELSKALDLWARNSKLTFQEVNSDRADILVYFHRGSHGDGYPFDGRGQILAHAFFPGKDRGGDAHFDEEEIWYLQDNSNEDGTSLFAVAAHEFGHSLGLAHSSVQGALMYPWYQGLSPNYELPEDDRHGIQQMYGAPEERLWGNIPGGPPPPERPTPATTTTTVATTYRPSRTRPTRPNHYPDYGRPRRPDRYPSKPDYRTERPDYRPQRPHKPHRHHTTTLATTTTTVRPTFQRPRFRWTPPPRHDVPDKCNTSYDAISIIRREVFIFKGRYLWRIGDQGLYEGYPAEITRLFNLPEDIDHVDAVYERPDKKIVFFIGKKYYVFNANNLEPGYPRPLTILGLPASLEKIDGAMVWGHNSRTYFFSGSMYWRFDESVNHVELDYPRDISSNFVGVGNDIDAVFQWKDGKTYFFKGKGFWLFDDLRMKVAHEKQKLSAPFWMGCPRTLETNDVENNIPKKAKITSSAADSVLVSRFSMGAIVIIVAFVSVFA

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias294-310Polar residues
Compositional bias315-345Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAIFRP010000038
EMBL· GenBank· DDBJ
KAK2581758.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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