A0AAD9MZJ7 · A0AAD9MZJ7_9ANNE

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for binding site, active site.

117002004006008001,0001,2001,4001,600
TypeIDPosition(s)Description
Binding site257Zn2+ (UniProtKB | ChEBI); catalytic
Active site258
Binding site261Zn2+ (UniProtKB | ChEBI); catalytic
Binding site267Zn2+ (UniProtKB | ChEBI); catalytic

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmembrane
Molecular Functionmetalloendopeptidase activity
Molecular Functiontransmembrane signaling receptor activity
Molecular Functionzinc ion binding
Biological Processimmune response
Biological Processinflammatory response
Biological Processproteolysis
Biological Processtoll-like receptor signaling pathway

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Metalloendopeptidase
  • EC number

Gene names

    • ORF names
      LSH36_430g04084

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • P08H-3
  • Taxonomic lineage
    Eukaryota > Metazoa > Spiralia > Lophotrochozoa > Annelida > Polychaeta > Sedentaria > Canalipalpata > Terebellida > Terebelliformia > Alvinellidae > Paralvinella

Accessions

  • Primary accession
    A0AAD9MZJ7

Proteomes

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane1490-1514Helical

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain.

TypeIDPosition(s)Description
Signal1-20
ChainPRO_504177766121-1700Metalloendopeptidase

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain160-359Peptidase M12A
Domain381-507CUB
Region508-554Disordered
Compositional bias513-554Polar residues
Domain564-738VWFA
Domain756-927MAM
Domain1546-1689TIR

Sequence similarities

Belongs to the Toll-like receptor family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,700
  • Mass (Da)
    190,827
  • Last updated
    2024-05-29 v1
  • Checksum
    028E98444378F899
MMEIFGVLIVFYAILLGAEARSLLGHNYRGTWKPDNGETREEWLRCHGFRCKTWDDTRRKLEEFKAILAKANNKTDVSDTLVAVVKMVDSGSDDSLDGCIWLTGDQLDQTMAEIRNRSRARNAINRIQIVDGSRRHRNRNKHNRHKKTGHHGIHKRKVTNFRKYPITKWTTKTIHWKFDGQHSEEEREIIRGAFSHWQQQTCLTFNELGTIEPYTDNHILVTRQATGCHSFVGRITTIPQQLNLQRACLYNLGTPVHEIGHALGLWHEQQRSDRDSAIRVLWENLGYYVGQFYKGDTNNLTPYDYGSVMHYGPKDGSINAENTMETLNPWYHHNLGQRTGLSFLDAKAINMAYCQDACSDPLVRCQHGGYQDPNNCSRCKCPDGLGGVFCDKVAPPENESPGYKQGGPYPNHITCSWIVKVLQGSRISLKFEGEFAVYAYYQEQCHHWVEVKYKQDIGAEGPRFCGNRLPNDTIISEGEEMLIIFKSNWTDDGLYSRIGFRAKLEKVDPGDGTATTSAASSTTTTTTTPTRRTTTVTTPTTTTTTSTTRATTTTTSSNDCQVVDVVLVIDSSDNVIRNNWYKIIMFVNSIISQFNVALPAVHVGVIIYATHADIVLPLDGYDSISDVTKVVDAIRFLGGATNTDSGLSVMRSQFSSLGRLNAAKIAILITDGKSSEPKLAIEQASLAKSEGIRLYVAGLGENFDYSEAANLVGDHKHIIQIGAFEELDSPIFNYGDTVHEVVCFGGVTQTTSDLSWSCDFEDEAHPFCQMIQDRTLDQFDWIHQSGRTPSESTGPTEAYNGRYYAYVEASDPRKPGDEAILYLPKFNAEGKHCLSFAYSMFGFHIRTLQIAIKTRSGSIMPVWLLTGEQGEHWQTADVSINLQKDDQITIIGKRGDAYSGDIAIDDIHIRGGNDPRISWGRQIDCRRLGIANIPTGLPTVNVTSLLLGRNNIELVKYDDFKNFTDLRYLDLSSNQIGNISDDAFAGVRELIHLNLNFNRLLKWPGNAVSGLIRLKELYLDGATDITLGPLPPGFGDLTKLEKLVISDLRFGVISDEFFSKAAVSSVTFLDMSACTIDGVELGAFRNFTNIRTLKLNVVVGLNPTFLGNIMSDLDNTSLAVLDLFGTDGINKIDKSPFANFQHNVLKTLVLSYSAVGAIYPGAFRNLASLRELHLDYTELKEIKANCFNGLKSLTYLDVSGTKLNRYNFSGSELKNLKLLNVSYSSYLFHMKSRGFDRLGSLTELILENTNVEILEACVFCGLPNLTKLRMTYSNFERVDSNAFAGLTSLEVLDLTSSGIGYLNQSLFNSMTSLKSLTLDNNNFSQSGSVSADVFRILPNLTYLSMEFCQLSSDCGLFHHLTMLHTVTLNGNIGIQFSEHAFLGSSNLTTLVLSFTNTTTFLPSALNDLMLDYLDVSFDGLANISKMNVSYLHSAKLRRFAGRENPYSCSCENLNFLIWFNKTNKVADSRDLYYCGDQLLVQFDVRKCTNMLSFIFSVTTSLVLIATVGILVAYLNRWYVYYIWYKLCRKAFNKLEMEEEKKIRDEAEYDAFISCTYKGAEFVLNHLIDKLENGPIGDQRFKLLFEERDFDLGVSKAEAIYSAVKSSRKTIIILTDDYIDEEWKMYEYETAYSRISKKERVVIVVLLGVGKMGKLPQTLVGLLSSDDCIEWPEEDKQGQEVFWQCLKDALNRPTFVGPTTV

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias513-554Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAODUP010000430
EMBL· GenBank· DDBJ
KAK2149948.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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